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Author: search.filters.author.Poeaim, S.Subject: search.filters.subject.Bioactivity

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    Influence of leaf type, genotype, and location on bioactivities and assessment of genetic diversity in teak (Tectona grandis L. f.)
    (2026-03-01)
    Poeaim, S.
    ;
    Phonmakham, J.
    Marked variation in biological activities was observed among teak (Tectona grandis L. f.) leaf extracts as influenced by leaf type, tree genotype, and planting location. Fresh leaves generally exhibited stronger antibacterial activity than fallen leaves, with significant differences detected among plus trees originating from Chiang Mai, Phrae, Sukhothai, Lampang, and Khon Kaen and grown at the Thongphaphum and Phitsanulok Silviculture Research Stations. Among all samples, the Phrae plus tree cultivated at Thongphaphum showed the highest antibacterial inhibition against the tested microorganisms. Methanol extracts demonstrated antibacterial, anti-tyrosinase, and anti-inflammatory activities, while sequential extraction of Phrae plus tree leaves using hexane and dichloromethane yielded fractions with potent antibacterial effects, indicating promising potential for the development of new antibacterial agents. Genetic analysis based on sequence-related amplified polymorphism (SRAP) markers revealed similarity coefficients ranging from 0.67 to 1.00, reflecting low to moderate genetic diversity among the studied germplasm, with some samples exhibiting nearly identical genetic profiles. Overall, the observed variation in biological activities was closely associated with both genetic background and environmental conditions, providing valuable information for teak germplasm selection and the utilization of leaf-derived bioactive compounds in product development.
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    The bioactivities of seed coat and embryo extracts from indian gooseberry (Phyllanthus emblica)
    (2018-03-01)
    Jaiboonma, A.
    ;
    Janvikul, W.
    ;
    Poeaim, S.
    The research evaluated the bioactivities of seed coat and embryo extracts from Indian gooseberry (Phyllanthus emblica Linn). The crude methanolic extract was further successively extracted with hexane, ethyl acetate, n-butanol and water by liquid-liquid partitioning method. The total phenolic content (TPC) in each solvent-extracted fraction was determined by Folin-Ciocateu method. The ethyl acetate seed coat extract possessed the highest TPC with values of 439.09±5.49 milligrams gallic acid equivalent (mgGAE)/g extract. The antioxidant activity of each extract was examined using ferric-reducing antioxidant power (FRAP) and 2, 2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+) assay. The ethyl acetate seed coat extract revealed 50% inhibitory concentration (IC <inf>50</inf> value) at a concentration of 31.53±0.36 microgram/milliliter (μg/ml) and ferric-reducing antioxidant power with 751.92±5.22 milligrams ascorbic acid equivalent (mgAAE)/g extract. The antibacterial activity of each extract was performed using disc diffusion method. The ethyl acetate seed coat extract demonstrated the greatest bacterial inhibition against Bacillus subtilis ATCC 6633, Bacillus cereus DMST 5040, Staphylococcus epidermidis ATCC 12228, Staphylococcus aureus TISTR 1466, and Micrococcus luteus ATCC 9341. These results suggested that the seed coat extracted with ethyl acetate could be served as a natural source of the bioactive compounds and used in the preparations of products such as drugs, anti-aging supplements, and cosmetics.