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Item type:Publication, Assessing the Impact of Tourism Industry Transformation on Problem-Based Learning in Chinese Vocational Undergraduate Education(2024-01-01) ;Wen, JingSumettikoon, PiyapongPurpose: Within the swiftly evolving landscape of the tourism sector, propelled by advancements in technology and evolving market forces, there arises an imperative to scrutinize their effects on vocational education. Methodology: This study investigates the influence of the transformation of tourism enterprises on problem-based learning (PBL) and academic achievement among Chinese vocational undergraduate students. It delves into the mediating role of instructor assistance and the moderating effect of student motivation. Analysis: Utilizing a quantitative research design, the researchers administered questionnaires to 450 participants enrolled in vocational institutions in China, achieving a response rate of 71%. The questionnaire encompassed items gauging perceptions of enterprise transformation, the efficacy of PBL, student academic performance, instructor support, and student motivation. Data analysis involved regression, mediation, and moderation analyses utilizing SPSS software. Findings: The results indicate a significant correlation between the transformation of the tourism industry and the efficacy of PBL, resulting in enhanced student performance. Teacher assistance substantially mediates these connections, amplifying the influence of enterprise adaptations on academic outcomes. Additionally, student motivation has been observed to marginally attenuate the effectiveness of PBL while exerting a direct impact on student performance, with higher motivation levels correlating with better outcomes. Future Directions: This study enriches our comprehension of how evolving industry demands impact academic methodologies within vocational contexts. It underscores the importance of synchronizing educational curricula with industry transformations and emphasizes the pivotal roles played by teacher assistance and student motivation in maximizing learning outcomes. These insights hold significant value for educators, policymakers, and industry stakeholders striving to enhance vocational education's adaptability to industry requisites. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Cultivating Change: The Mediating Roles of Knowledge and Skills in the Relationship between Tourism Education Interventions and Industry Transformation(2023-01-01) ;Wen, JingSumettikoon, PiyapongPurpose: In the ever-evolving world of the global tourism sector, the significance of education in moulding a competent and well-informed workforce has been on the rise. Interventions in education impacting various aspects of change in the tourism industry. This research aims to explore the complex relationships among education interventions, knowledge acquisition, skills development, and tourism transformation. Through exploring the mediating roles of knowledge and skills in this connection, the research seeks to offer a detailed comprehension of how education supports sustainable practices, cultural preservation, and the successful integration of digital technologies in the tourism sector. Method: Using a quantitative research design, this study gathered data from a sample of tourist workers in China. Analysed responses of participants were examined to investigate the connections among education interventions, knowledge acquisition, skills development, and tourism transformation. The study employed well-known scales to assess the main variables, and utilised statistical methods, such as mediation analysis, to investigate the mediating functions. Findings: The research findings suggest a strong correlation between tourism education interventions and tourism transformation. Moreover, the research reveals the mediating roles of knowledge acquisition and skills development in this correlation, emphasising the broad impact of education on various aspects of change in the tourism industry. Implications for Research and Practice: This study fills gaps in current literature and provides a comprehensive perspective on the relationships being studied. The study is notable for its thorough examination, which encompasses not just the immediate effects of education interventions but also the intermediary functions of knowledge and skills. The study's results have significant implications for policymakers, educators, and industry professionals. They highlight the importance of prioritising education to drive positive developments in sustainability, cultural preservation, and technology integration in the global tourism sector. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The clonal repopulation of HSPC gene modified with anti-HIV-1 RNAi is not affected by preexisting HIV-1 infection(2020-07-01) ;Suryawanshi, Gajendra W. ;Khamaikawin, Wannisa ;Wen, Jing ;Shimizu, SakiArokium, HubertDespite advances in hematopoietic stem/progenitor cell (HSPC) transplant for HIV-1-infected patients, the impact of a preexisting HIV-1 infection on the engraftment and clonal repopulation of HSPCs remains poorly understood. We have developed a long terminal repeat indexing-mediated integration site sequencing (LTRi-Seq) method that provides a multiplexed clonal quantitation of both anti-HIV-1 RNAi (RNA interference) gene-modified and control vector-modified cell populations, together with HIV-1-infected cells-all within the same animal. In our HIV-1-preinfected humanized mice, both therapeutic and control HSPCs repopulated efficiently without abnormalities. Although the HIV-1-mediated selection of anti-HIV-1 RNAi-modified clones was evident in HIV-1-infected mice, the organ-to-organ and intra-organ clonal distributions in infected mice were indistinguishable from those in uninfected mice. HIV-1-infected cells showed clonal patterns distinct from those of HSPCs. Our data demonstrate that, despite the substantial impact of HIV-1 infection on CD4<sup>+</sup> T cells, HSPC repopulation remains polyclonal, thus supporting the use of HSPC transplant for anti-HIV treatment.
