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Author: search.filters.author.Wuttanachamsri, KanognudgeSubject: search.filters.subject.Moving solid phases

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    The Flow in Periciliary Layer in Human Lungs with Navier-Stokes-Brinkman Equations
    (2021-11-10)
    Oangwatcharaparkan, Nattapol
    ;
    Wuttanachamsri, Kanognudge
    In the human respiratory tract, air breathed in is often contaminated with strange particles such as dust and chemical spray, which may cause people respiratory diseases. However, the human body has an innate immune system that helps to trap the debris by secreting mucus to catch the foreign particles, which are removed from the body by the movement of tiny hairs lining on the surface of the epithelial cells in the immune system. The layer containing the tiny hairs or cilia is called Periciliary Layer (PCL). In this research, we find the velocity of the fluid in the PCL moved by a ciliary beating by using the Navier-Stokes-Brinkman equations. We apply the Galerkin finite element method to determine numerical solutions. For the steady linear case of the equation, the numerical result is in good agreement with an exact solution. Including the time derivative and nonlinear terms, we show that the velocity of the liquid is affected by the velocity of the solid, which follows the physical meaning of the fluid flow. The result can be applied as a bottom boundary condition of the mucous layer to be able to find the velocity of mucus in the human lungs.
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    The velocity of PCL fluid in human lungs with beaver and Joseph boundary condition by using asymptotic expansion method
    (2019-01-01)
    Poopra, Sudaporn
    ;
    Wuttanachamsri, Kanognudge
    Humans breathe air into the respiratory system through the trachea, but with all the pollutants in our environment (both outside and inside), the air we breathe may not be clean. When that is so, the respiratory system secretes mucus to trap dirt that is inhaled through the nostrils. The respiratory tract contains hair-like structures in the epithelial tissue, called cilia: These wave back and forth to help expel particles of dust, dirt, mucus, and contaminants from the body. Cilia are found in this layer (a porous medium) and the fluid in this layer is called the periciliary layer (PCL). This study aims to determine the velocity of the PCL fluid flow in motile cilia. Usually, fluids move due to pressure changes, but in this study, the velocity of solids or of the cilia moves the PCL fluid. Stokes-Brinkman equations are used to determine the velocity of PCL fluid flow when cilia form an angle with the horizontal plane. The Beavers and Joseph boundary condition is applied in this study. The asymptotic expansion method is adapted in order to determine the velocity of PCL from the movement of the cilia.