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    The prevalence of capripoxvirus causing lumpy skin disease in beef cattle with no clinical signs on a well-managed cooperative farm
    (2025-03-01)
    Kaewhom, P.
    ;
    Poolsamran, P.
    ;
    Ard-Rugsa, T.
    ;
    Phromnoi, S.
    ;
    Thammakarn, C.
    Capripoxviruses were confidently detected in cattle, exhibiting a prevalence of 1.17% (9 out of 770 samples). The PCR products from the infected cattle consistently ranged from 1,000 to 1,500 base pairs, even at very low viral loads. Importantly, no significant differences in infection rates were found between the summer and rainy seasons (P > 0.05), and the prevalence was not associated with specific geographical regions or the timing of blood sample collection (P > 0.05). Notably, infected cattle displayed no clinical signs, such as skin nodules, emphasising that the disease can be present without causing visible harm. These findings strongly reinforce the necessity for stringent disease prevention measures in beef cattle production to effectively mitigate potential losses.
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    Dengue viremia kinetics in asymptomatic and symptomatic infection
    (2020-12-01)
    Matangkasombut, Ponpan
    ;
    Manopwisedjaroen, Kajohnpong
    ;
    Pitabut, Nada
    ;
    Thaloengsok, Sasikanya
    ;
    Suraamornkul, Swangjit
    Background: Dengue infection is a global health threat. While symptomatic cases contribute to morbidity and mortality, the majority of infected people are asymptomatic but serve as an important reservoir. However, the kinetics of viremia in asymptomatic infections remains unknown. Methods: We enrolled 279 hospital-based symptomatic index cases and quantified dengue virus (DENV) RNA at enrollment and at the day of defervescence. To identify asymptomatic cases, 175 household members of index cases were monitored for clinical symptoms during follow-up, and blood was taken twice weekly to test for and quantify DENV RNA until cleared. Results: We detected DENV in thirteen asymptomatic household members (7.43%). Their DENV serotypes were primarily the same as those of their family index cases. The median peak DENV viremia in asymptomatic subjects was lower than that of symptomatic individuals during the febrile phase, and the viral decay rate was slower in asymptomatic infections. Conclusions: DENV level and kinetics in asymptomatic individuals differed significantly from those of symptomatic cases. Despite the lower viremia, the slower decay rate in asymptomatic infections could lead to their prolonging the infectious reservoir. The improvement of transmission control to prevent such long-lived asymptomatic infections from transmitting the DENV is needed.
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    Mathematical model of the symptomatic and asymptomatic infections of swine flu
    (2011-01-06)
    Pongsumpun, P.
    ;
    Tang, I. M.
    Swine flu (swine influenza) is a respiratory disease caused by type A influenza. This disease is transmitted between the persons through coughing or sneezing with the virus. Persons may also become infected by touching something, contaminated with flu virus and then touching their eyes, nose or mouth. The most common clinical findings are fever, cough, sore throat, malaise, headache, vomiting and diarrhea have also been common, both of which are unusual features of seasonal influenza. In this paper, the transmission of Swine flu is studied through standard dynamical modeling method. The symptomatic and asymptomatic patients are considered with the different transmission rates. The analytical solutions of the model are obtained. The numerical simulations are shown to support the theoretical predictions. The basic reproductive number is produced for introducing the alternative way to decrease the disease outbreak.