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Subject: search.filters.subject.Garcinia cowa

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    Research Article Biosynthesis of Silver Nanoparticles Using Garcinia cowa Aqueous Leaf Extract and Their Antifungal Activity Against Durian Dieback Pathogen
    (2023-09-01)
    Sukkha, Usa
    ;
    Khejonrak, Awadol
    ;
    Kamonpha, Phitsamai
    ;
    Ruangvittayanon, Anuchit
    ;
    Pakdeepromma, Sirichatnach
    Silver nanoparticles (AgNPs) were synthesized under different pH and reaction time using the Garcinia cowa aqueous leaf extract. The formation, crystal structure and morphology of synthesized AgNPs were investigated using UV-Vis spectroscopy, X-ray diffraction (XRD) and transmission electron microscopy (TEM) techniques. The UV-Vis result indicated that the AgNPs were synthesized using Garcinia cowa aqueous leaf extract at all pH conditions within 10 min. The synthesis of AgNPs was significantly affected by pH condition which was shown by the TEM micrographs. The particle sizes of AgNPs were in a nano-sized range; 6.30 ± 3.52 nm for pH 4, 3.87 ± 2.51 nm for pH 7 and 13.97 ± 11.84 nm for pH 10. Furthermore, the AgNPs prepared in pH 4, pH 7 and pH 10 (120 min reaction time) at different concentrations were assessed for their antifungal activity against durian dieback pathogen. It was found that the 800 mL/L of AgNPs prepared at pH 7, the smallest particle size and good dispersion, showed the highest inhibition mycelial growth at 47.33%, whereas the larger nanoparticles prepared at pH 4 and pH 10 conditions showed lower inhibition of mycelial growth at 43.22% and 32.55%, respectively.
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    Antimicrobial, antioxidant and anticancer activities of Thai local vegetables
    (2009-12-01)
    Nanasombat, S.
    ;
    Teckchuen, N.
    Thai local vegetables (20 species) were screened for their antimicrobial and antioxidant activities. Methanolic extracts of Cassia siamea, Garcinia cowa, Limnophila aromatica and Polygonum odoratum exhibited strong antioxidant and antibacterial activities. The sensitive bacteria to these extracts were Bacillus cereus, Listeria monocytogenes and Staphylococcus aureus. Among all plant extracts, the extract of P. odoratum had the highest phenolic content and antioxidant activity with EC <inf>50</inf> value of 315.35 μg extract/mg DPPH (2,2-diphenyl-1-picrylhydrazyl). These plant extracts were also tested for cytotoxicity against human oral epidermal carcinoma (KB), breast adenocarcinoma (MCF-7) and small cell lung carcinoma (NCI-H187). P. odoratum extract was moderately active against MCF-7 (IC <inf>50</inf> value of 6.01 μg/ml). Major types of active compounds in P. odoratum extract were identified by HPLC method. Flavonoids found in this plant were rutin, catechin, quercetin, kaempferol and isorhamnetin. Among these compounds, rutin was found in the highest amount (3.77% w/w dry extract). © 2009 Academic Journals.