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    Item type:Publication,
    Low-cost instrumentation of Automated Whole - Slide Microscope for Biomedical Imaging
    (2019-01-10)
    Pechprasarn, Suejit
    ;
    Sukkasem, Chayanisa
    ;
    Suvarnaphaet, Phitsini
    ;
    Thongchoom, Rujirada
    ;
    Chuwittaya, Suteeboon
    Microscope is one of the essential devices in medical profession. It is usually used for finding out types of abnormal cells or tissues, detecting the diseases, and defining a range treatment option for patient. Recently, there is a new technology of whole-slide imaging (WSI) which has been developed in the microscope. The technology provides the scanning of conventional glass slides to produce digital images of cumulative data. Since the WSI is a complex system and very expensive price, hence we aim to implement the prototype of a cost- effective whole - slide imaging system based on the principle of microscopic design. The implemented prototype consisting of optical and mechanical parts was developed using 3D printing. The optical system employed a 40x objective lens aligning with the digital camera for imaging the specimen on the standard slide. The mechanical system was designed for the movement of the slide in 3 dimensions automatically and controlled by stepper motors and microcontrollers based on controlling computer program. To accumulate the whole- slide image, the slide was scanned and captured in the X-Y axes and the focal (Z) axis in a sequence. The cumulative data was then analyzed and rendered the whole- slide image. The implemented device would be advantageous to cytologists and doctors for the biomedical imaging and recording numerous medical data of the patients.