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Author: search.filters.author.Haemmerich, DieterSubject: search.filters.subject.Ablation

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    Finite-element analysis of hepatic multiple probe radio-frequency ablation
    (2002-07-30)
    Haemmerich, Dieter
    ;
    Tungjitkusolmun, Supan
    ;
    Staelin, S. Tyler
    ;
    Lee, Fred T.
    ;
    Mahvi, David M.
    Radio-frequency (RF) ablation is an important means of treatment of nonresectable primary and metastatic liver tumors. RF ablation, unlike cryoablation (a method of tumor destruction that utilizes cold rather than heat), must be performed with a single probe placed serially. The ablation of any but the smallest tumor requires the use of multiple overlapping treatment zones. We evaluated the performance of a configuration incorporating two hooked probes (RITA model 30). The probes were lined up along the same axis in parallel 20 mm apart. Three different modes applied voltage to the probes. The first mode applied energy in monopolar mode (current flows from both probes to a dispersive electrode). The second mode applied the energy to the probes in bipolar mode (current flows from one probe to the other). The third method applied the energy sequentially in monopolar mode (in 2-s intervals switched between the probes). We used the finite-element method (FEM) and analyzed the electric potential profile and the temperature distribution at the end of simulation of a 12-min ablation. The alternating monopolar mode allowed precise independent control of the amount of energy deposited at each probe. The bipolar mode created the highest temperature in the area between the probes in the configuration we examined. The monopolar mode showed the worst performance since the two probes in close vicinity create a disadvantageous electric field configuration. We, thus, conclude that alternating monopolar RF ablation is superior to the other two methods.
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    Flow effect on lesion formation in RF cardiac catheter ablation
    (2001-04-23)
    Cao, Hong
    ;
    Vorperian, Vicken R.
    ;
    Tungjitkusolmun, Supan
    ;
    Tsai, Jang Zern
    ;
    Haemmerich, Dieter
    This study investigated the flow effect on the lesion formation during radio-frequency cardiac catheter ablation in temperature-controlled mode. The blood flow in heart chambers carries heat away from the endocardium by convection. This cooling effect requires more power from the ablation generator and causes a larger lesion. We set up a flow system to simulate the flow inside the heart chamber. We performed in vitro ablation on bovine myocardium with three different flow rates (0 L/min, 1 L/rain and 3 L/min) and two target temperatures (60 °C and 80 °C). During ablation, we also recorded the temperatures inside the myocardium with a three-thermocouple temperature probe. The results show that lesion dimensions (maximum depth, maximum width and lesion volume) are larger in high flow rates (p < 0.01). Also, the temperature recordings show that the tissue temperature rises faster and reaches a higher temperature under higher flow rate.