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    Explainable AI (XAI) for Breast Cancer Diagnosis
    (2024-01-01)
    Ariyametkul, Awika
    ;
    Tamang, Sudarshan
    ;
    Paing, May Phu
    Breast cancer is the leading cause of mortality and incidence among women worldwide. Mammography, an essential imaging technique, plays a pivotal role in both screening and diagnostic processes by facilitating early detection, which helps improve survival rates. Despite its effectiveness, interpreting mammographic images presents considerable challenges, necessitating the expertise of highly trained radiologists. Artificial intelligence (AI) is a powerful tool for managing large amounts of data and is increasingly used across numerous sectors, including medical applications. This research focuses on applying Convolutional Neural Networks (CNNs) to classify breast cancer from mammograms. We explored six different CNN models including simple ConvNet, AlexNet, VGG-16, GoogLeNet, XceptionNet, and DenseNet201. Our results indicate that DenseNet201 is the most suitable model for this task, achieving 99% accuracy. However, a limitation of AI is the lack of transparency and explanation, often referred to as the 'black box' problem. This vulnerability can be addressed through explainable artificial intelligence (XAI), which elucidates the processes behind AI's decision-making. We employed three different XAI methodologies, including LIME, GradCAM, and GradCAM++, to visualize the model's decision-making process.
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    Adenoma Dysplasia Grading of Colorectal Polyps Using Fast Fourier Convolutional ResNet (FFC-ResNet)
    (2023-01-01)
    Paing, May Phu
    ;
    Pintavirooj, Chuchart
    Colorectal polyps are precursor lesions of colorectal cancer; hence, early detection and dysplasia grading of polyps are essential for determining cancer risk, the possibility of developing subsequent polyps, and follow-up recommendations. The significant contribution of this study is the development of an enhanced deep-learning model called Fast Fourier Convolutional ResNet (FFC-ResNet) to classify dysplasia grades of polyps. It is based on the ResNet-50 architecture and uses cross-feature fusion, which combines local features extracted by traditional spatial convolution with global features extracted by Fourier convolution. Due to the compensatory effect between local and global features, the learnability and performance of FFC-ResNet have increased. The proposed FFC-ResNet was developed and tested using UniToPatho, a dataset containing 7000 μm and 800 μm hematoxylin-and-eosin (H&E)-stained colorectal images. And a favorable performance of sensitivity 0.95, specificity 0.93, balance accuracy 0.94, precision 0.95, F1 score 0.95, and AUC 0.99 was obtained using 800 μm polyp patches.
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    Classification of White Blood Cells: A Comprehensive Study Using Transfer Learning Based on Convolutional Neural Networks
    (2022-12-01)
    Tamang, Thinam
    ;
    Baral, Sushish
    ;
    Paing, May Phu
    White blood cells (WBCs) in the human immune system defend against infection and protect the body from external hazardous objects. They are comprised of neutrophils, eosinophils, basophils, monocytes, and lymphocytes, whereby each accounts for a distinct percentage and performs specific functions. Traditionally, the clinical laboratory procedure for quantifying the specific types of white blood cells is an integral part of a complete blood count (CBC) test, which aids in monitoring the health of people. With the advancements in deep learning, blood film images can be classified in less time and with high accuracy using various algorithms. This paper exploits a number of state-of-the-art deep learning models and their variations based on CNN architecture. A comparative study on model performance based on accuracy, F1-score, recall, precision, number of parameters, and time was conducted, and DenseNet161 was found to demonstrate a superior performance among its counterparts. In addition, advanced optimization techniques such as normalization, mixed-up augmentation, and label smoothing were also employed on DenseNet to further refine its performance.
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    Automated Caries Screening Using Ensemble Deep Learning on Panoramic Radiographs
    (2022-10-01)
    Bui, Toan Huy
    ;
    Hamamoto, Kazuhiko
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    Paing, May Phu
    Caries prevention is essential for oral hygiene. A fully automated procedure that reduces human labor and human error is needed. This paper presents a fully automated method that segments tooth regions of interest from a panoramic radiograph to diagnose caries. A patient’s panoramic oral radiograph, which can be taken at any dental facility, is first segmented into several segments of individual teeth. Then, informative features are extracted from the teeth using a pre-trained deep learning network such as VGG, Resnet, or Xception. Each extracted feature is learned by a classification model such as random forest, k-nearest neighbor, or support vector machine. The prediction of each classifier model is considered as an individual opinion that contributes to the final diagnosis, which is decided by a majority voting method. The proposed method achieved an accuracy of 93.58%, a sensitivity of 93.91%, and a specificity of 93.33%, making it promising for widespread implementation. The proposed method, which outperforms existing methods in terms of reliability, and can facilitate dental diagnosis and reduce the need for tedious procedures.
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    Tooth Localization using YOLOv3 for Dental Diagnosis on Panoramic Radiographs
    (2022-01-01)
    Bui, Toan Huy
    ;
    Hamamoto, Kazuhiko
    ;
    Paing, May Phu
    Oral health is one of most major concerns that affect the life quality of billions of people around the world. Diagnosis treatment usually takes time due to the lack of doctors compared to a huge number of patients. Many researchers proposed methods to make an early disease detection for patients to assist doctors using computer aid diagnosis (CAD). However, most previous methods are not end-to-end methods and still require human involvement. The biggest challenge is that most researchers do not provide a good tooth detection technique before diagnosis. Therefore, the main objective, that builds a system to assist doctors, remains unaccomplished or just fairly successful. This paper proposed a detection method to localize the tooth using the Yolov3 model as a base network in the dental panoramic radiograph. The method consists of two main parts: image preprocessing and tooth localization. Firstly, because deep learning requires a big dataset, the original image is applied augmentation technique to improve the size of the dataset as well as diversity. Then, each image is resized to fit the input layer of the network; however, to prevent the information loss and boost the performance, we keep the original ratio of the images and change the ratio of the input layer in the model that can fit the image ratio. Next, we feed images into Yolov3, which is specially modified to fit the problem, for training. We add more detection heads into the backbone and concatenate the previous head detection’s result with a proper layer to produce a more preeminent result. The final assessment shows an impressive result that the method reaches 95.58% and 94.90% for precision and recall, respectively. As a result, our proposed method is more reliable and practical in the tooth localization field, as well as helpful to reduce the doctor's effort.