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Author: search.filters.author.Piyawattanametha, WiboolSubject: search.filters.subject.Confocal

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    Metalens-based miniaturized optical systems
    (2019-05-01)
    Li, Bo
    ;
    Piyawattanametha, Wibool
    ;
    Qiu, Zhen
    Metasurfaces have been studied and widely applied to optical systems. Ametasurface-based flat lens (metalens) holds promise in wave-front engineering for multiple applications. The metalens has become a breakthrough technology for miniaturized optical system development, due to its outstanding characteristics, such as ultrathinness and cost-effectiveness. Compared to conventional macro- or meso-scale optics manufacturing methods, the micro-machining process for metalenses is relatively straightforward and more suitable for mass production. Due to their remarkable abilities and superior optical performance, metalenses in refractive or diffractive mode could potentially replace traditional optics. In this review, we give a brief overview of the most recent studies on metalenses and their applications with a specific focus on miniaturized optical imaging and sensing systems. We discuss approaches for overcoming technical challenges in the bio-optics field, including a large field of view (FOV), chromatic aberration, and high-resolution imaging.
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    MEMS actuators for optical microendoscopy
    (2019-01-24)
    Qiu, Zhen
    ;
    Piyawattanametha, Wibool
    Growing demands for affordable, portable, and reliable optical microendoscopic imaging devices are attracting research institutes and industries to find new manufacturing methods. However, the integration of microscopic components into these subsystems is one of today's challenges in manufacturing and packaging. Together with this kind of miniaturization more and more functional parts have to be accommodated in ever smaller spaces. Therefore, solving this challenge with the use of microelectromechanical systems (MEMS) fabrication technology has opened the promising opportunities in enabling a wide variety of novel optical microendoscopy to be miniaturized. MEMS fabrication technology enables abilities to apply batch fabrication methods with high-precision and to include a wide variety of optical functionalities to the optical components. As a result, MEMS technology has enabled greater accessibility to advance optical microendoscopy technology to provide high-resolution and high-performance imaging matching with traditional table-top microscopy. In this review the latest advancements of MEMS actuators for optical microendoscopy will be discussed in detail.
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    MEMS based fiber optical microendoscopes
    (2015-01-01)
    Qiu, Zhen
    ;
    Piyawattanametha, Wibool
    Fiber-optical microendoscopy has recently been an essential medical diagnostic tool for patients in investigating tissues in vivo due to affordable cost, high quality imaging performance, compact size, high-speed imaging, and flexible movement. Microelectromechanical systems (MEMS) scanner technology has been playing a key role in shaping the miniaturization and enabling high-speed imaging of fiber-optical microendoscopy for over 20 years. In this article, both review of MEMS based fiber-optical microendoscopy for optical coherence tomography, confocal, and two-photon imaging will be discussed. These advanced optical endoscopic imaging modalities provide cellular and molecular features with deep tissue penetration enabling guided resections and early cancer assessment.