Dejtisakdi, Wipawee
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Preferred name
Dejtisakdi, Wipawee
Alternative Name
Dejtisakdi, W.
Main Affiliation
Email
wipawee.de@kmitl.ac.th
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Item type:Publication, INVESTIGATION OF ANTIFUNGAL ACTIVITY FROM SCENEDESMUS SP. AND CHLAMYDOMONAS SP. CRUDE EXTRACTS(2022-01-01); Scenedesmus sp. and Chlamydomonas sp. are green microalgae used for various biotechnology applications such as an alternative biofuel, antioxidant, human supplement, aquaculture feed etc. In a decade, finding a new antibiotic resource from a novel organism is significant for pharmaceutical research. Microalgae is a promising candidate since they consist of high-value biocompounds such as β-carotene, astaxanthin, flavonoids, polysaccharide. In this study, we aimed to preliminarily investigate antifungal activities of Scenedesmus and Chlamydomonas crude extracts against to Candida albicans, a fungal pathogen. We prepared both of intracellular and extracellular (culture media) crude extracts by using ethanol and methanol as a solvent and then tested C albicans inhibition performed by agar-well diffusion assay. From the preliminary results, we found that 50 mg/mL of Scenedesmus and Chlamydomonas ethanolic crude extracts from intracellular and extracellular could inhibit C. albicans. This preliminary finding could be a platform for a further study in some bio-based organic compounds that is significant for pharmaceutical application.