Soonwera, Mayura

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Preferred name
Soonwera, Mayura
Alternative Name
Soonwera, M.
Main Affiliation
Email
mayura.so@kmitl.ac.th

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    Efficacy of new herbal shampoos from garcinia dulcis kurz, citrus aurantium l. and eucalyptus globulus labill as pediculicides for head lice (Pediculus humans capitis) control
    (2018-07-01)
    Sittichok, S.
    ;
    Soonwera, M.
    Currently, synthetic chemical pediculicides have lost their efficacy due to worldwide increased resistance of head lice to them. Therefore, safe, natural product alternatives are in dire need. This study investigated the efficacy of an herbal shampoo made from Garcinia dulcis (Roxb.) added with either Citrus aurantium EO or Eucalyptus globulus EO against head lice in both in vitro and in vivo tests. In vitro experiment used a filter paper contact method to evaluate the pediculicidal activity of the shampoo at 0.002, 0.003 and 0.006 ml/cm <sup>2</sup> doses (per unit area of petri dish plate) on nymphs and adults of head lice. In vivo trial, the infested children were treated with the shampoo. The results showed either cured or not cured of pediculosis. The main results showed LC50 values against nymphs for G. dulcis + C. aurantium EO shampoo and G. dulcis + E. globulus EO shampoo were 0.00001 and 0.00004 ml/cm <sup>2</sup> , respectively. Those actively against the adults which were 0.7 and 0.9 ml/cm <sup>2</sup> , respectively. In vivo test revealed that G. dulcis + C. aurantium EO shampoo and G. dulcis + E. globulus EO shampoo were the most effective pediculicide, showing 100% cure rate after the 2nd application, much more effective than the tested chemical pediculicide. It concluded that these shampoos can be highly affected pediculicide alternatives and safe for treating humans.
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    Efficacy of Thai herbal shampoos from averrhoa carambola L., Hibiscus sabdariffa L. and Passiflora edulis Sims. for controlling head lice, pediculus humanus capitis (De Geer)
    (2018-09-01)
    Sittichok, S.
    ;
    Chantawee, A.
    ;
    Soonwera, M.
    Pediculosis is an infestation of the scalp caused by head lice, Pediculus humanus capitis (De Geer), which affects important public health in schoolchildren. Nowadays, head lice resistant to chemical pediculicide are increasing, thus alternative products from herbal shampoos or herbal cream are needed for head lice control. This study aimed to determine the efficacies of Thai herbal shampoos made from fruits of Averrhoa carambola L. (A. carambola), Hibiscus sabdariffa L. (H. sabdariffa) and Passiflora edulis Sims. (P. edulis) on mortality of head lice, at 1, 5 and 10 ml/plate by filter paper contact bioassay in vitro test and in vivo test, several infested children were treated with each shampoo and make a comparison between them and a chemical shampoo, carbaryl, by in vitro and in vivo tests. Every treatment was repeated three times. The in vitro results showed that the 5 and 10 ml/plate doses of P. edulis and H. sabdariffa shampoos exhibited the highest efficacy as pediculicide against nymphs with an LC <inf>50</inf> of 0.85 ml/plate and LT <inf>50</inf> between <0.1 to 0.20, and <0.1 to 0.47 min, respectively. LC <inf>50</inf> of P. edulis and H. sabdariffa shampoos against adults were 0.85 and 1.09 ml/plate, respectively, and LT <inf>50</inf> was between <0.1 to 0.83 min. From the in vivo test, P. edulis shampoo was found to be the most effective in controlling head lice with 100% cure rate after the 2nd treatment. It was more effective than carbaryl.In conclusion, P. edulis shampoo is an effective alternative as pediculicide for head lice treatment because it is safe: no side effects on the scalp of the subjects were observed.