Piyawattanametha, Wibool

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Editorial Special Issue on OMN 2022
(2023-08-15)
Piyawattanametha, Wibool
;
Ferhanoglu, Onur
;
Zhang, John X.J.
We are pleased to provide readers with the newest and important technologies presented at the International Conference on Optical MEMS and Nanophotonics 2022 (OMN 2022), through this Special Issue published by the IEEE Photonics Technology Letters (PTL) journal. The Optical Micro- and Nano Systems (OMN) conferences have surged in prominence over the recent years, mirroring the rapid advancements and burgeoning interest in the realm of optics and photonics technology for diverse applications from medical imaging, environmental sensing, to autonomous driving. OMN epitomizes the amalgamation of theory and practice, facilitated by our increasing technical prowess to engineer micro- and nano-scale structures and dynamic elements purpose-built for the interaction and manipulation of light.
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MEMS-Based Medical Endomicroscopes
(2015-07-01)
Qiu, Zhen
;
Piyawattanametha, Wibool
Progress toward early diagnosis of cancer would have significant clinical benefits in reducing mortality or prolonging life in cancer patients; thus, there is an important unmet clinical need to image cellular features of cancer in vivo and in real time to correlate pathological symptoms and underlying cells responsible for such symptoms. In this paper, we describe a review of microelectromechanical systems scanners-based endoscopic optical coherence tomography, confocal, two-photon, and photoacoustic microscopy imaging. These advanced optical imaging modalities can provide subcellular (micron-scale) resolution and deep tissue penetration to reveal both cells and molecular features for early cancer diagnosis, cancer staging, and surgical guidance.
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MEMS actuators for optical microendoscopy
(2019-01-24)
Qiu, Zhen
;
Piyawattanametha, Wibool
Growing demands for affordable, portable, and reliable optical microendoscopic imaging devices are attracting research institutes and industries to find new manufacturing methods. However, the integration of microscopic components into these subsystems is one of today's challenges in manufacturing and packaging. Together with this kind of miniaturization more and more functional parts have to be accommodated in ever smaller spaces. Therefore, solving this challenge with the use of microelectromechanical systems (MEMS) fabrication technology has opened the promising opportunities in enabling a wide variety of novel optical microendoscopy to be miniaturized. MEMS fabrication technology enables abilities to apply batch fabrication methods with high-precision and to include a wide variety of optical functionalities to the optical components. As a result, MEMS technology has enabled greater accessibility to advance optical microendoscopy technology to provide high-resolution and high-performance imaging matching with traditional table-top microscopy. In this review the latest advancements of MEMS actuators for optical microendoscopy will be discussed in detail.
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MEMS based fiber optical microendoscopes
(2015-01-01)
Qiu, Zhen
;
Piyawattanametha, Wibool
Fiber-optical microendoscopy has recently been an essential medical diagnostic tool for patients in investigating tissues in vivo due to affordable cost, high quality imaging performance, compact size, high-speed imaging, and flexible movement. Microelectromechanical systems (MEMS) scanner technology has been playing a key role in shaping the miniaturization and enabling high-speed imaging of fiber-optical microendoscopy for over 20 years. In this article, both review of MEMS based fiber-optical microendoscopy for optical coherence tomography, confocal, and two-photon imaging will be discussed. These advanced optical endoscopic imaging modalities provide cellular and molecular features with deep tissue penetration enabling guided resections and early cancer assessment.
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Metalens-based miniaturized optical systems
(2019-05-01)
Li, Bo
;
Piyawattanametha, Wibool
;
Qiu, Zhen
Metasurfaces have been studied and widely applied to optical systems. Ametasurface-based flat lens (metalens) holds promise in wave-front engineering for multiple applications. The metalens has become a breakthrough technology for miniaturized optical system development, due to its outstanding characteristics, such as ultrathinness and cost-effectiveness. Compared to conventional macro- or meso-scale optics manufacturing methods, the micro-machining process for metalenses is relatively straightforward and more suitable for mass production. Due to their remarkable abilities and superior optical performance, metalenses in refractive or diffractive mode could potentially replace traditional optics. In this review, we give a brief overview of the most recent studies on metalenses and their applications with a specific focus on miniaturized optical imaging and sensing systems. We discuss approaches for overcoming technical challenges in the bio-optics field, including a large field of view (FOV), chromatic aberration, and high-resolution imaging.
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Comparison of MEMS-based photoacoustic microscopy in biomedical imaging
(2025-01-01)
Suttikittipong, Pasin
;
Tangkiatphaibun, Parawee
;
Piyawattanametha, Nicholas
;
Piyawattanametha, Wibool
Photoacoustic microscopy (PAM) has emerged as a promising biomedical imaging technique, renowned for its capability to visualize the microvasculature and measure oxygen saturation levels in biological tissues, both non-invasively and in real-time. PAM combines the contrast benefits of optical imaging with the penetrating benefits of ultrasound. It offers high spatial resolution and deep tissue imaging, which is what microscopic and macroscopic imaging can’t do separately. This review presents fundamental knowledge of PAM’s theoretical model and the sensing mechanism. Using a Micro-Electro-Mechanical Systems or Microelectromechanical Systems (MEMS), various PAM optimizing techniques are covered, ranging from design, materials, and algorithms. Discussions also include opinions on future MEMS-based PAM technology development tendencies.

Piyawattanametha, Wibool

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