Teerasong, Saowapak
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Preferred name
Teerasong, Saowapak
Alternative Name
Teerasong, S.
Main Affiliation
Email
saowapak.te@kmitl.ac.th
2 results
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Item type:Publication, A new mechanism for resonance Rayleigh scattering detection of minoxidil based on catalytic oxidation of silver nanoparticles(2022-07-05); ; Chompoosor, ApiwatThis work presents a new method for minoxidil detection based on silver nanoparticle (AgNP) oxidation. Minoxidil, which is a pyrimidine N-oxide, can be reduced to its corresponding pyrimidine via a redox reaction. In this system, acetate buffer serves as a proton source. AgNPs act as electron donors that contribute electrons to the reaction, producing Ag<sup>+</sup>. Consequently, the sizes and numbers of AgNPs in the system decrease, which results in a decline in their resonance Rayleigh scattering (RRS). By monitoring the RRS intensity at 409 nm, a change in intensity was linearly related to the minoxidil concentration over a concentration range of 0.5 – 5.0 mM. The detection limit was 0.35 mM. This approach is simple and rapid. It is done by directly mixing the drug and AgNPs in an acidic buffer. The reaction was completed within 2 min. This proposed method was successfully utilized for quantification of minoxidil in topical hair-growth formulations. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Gold nanorods enhanced resonance Rayleigh scattering for detection of Hg2+ by in-situ mixing with single-stranded DNA(2018-02-01) ;Ngernpimai, Sawinee ;Matulakun, Piyaporn; ;Puangmali, TheerapongKopwitthaya, AtchaA resonance Rayleigh scattering (RRS) method for determination of Hg<sup>2+</sup> concentration using positively charged gold nanorods (GNRs) and thymine-rich single-stranded DNA (ssDNA) was developed. Hg<sup>2+</sup> can induce a conformation change of ssDNA from a random coil to a hairpin structure via thymine–Hg<sup>2+</sup>–thymine coordination. Hairpin shaped DNA possesses a high density of negative charges, therefore it caused in a drastic aggregation of GNRs. This resulted in an enhancement of RRS intensity. In this work, a change in RRS intensity proportional to the concentration of Hg<sup>2+</sup> was monitored by spectrofluorometer at excitation and RRS wavelengths of 550 nm (λ<inf>ex</inf> = λ<inf>RRS</inf>). This method offered a detection limit of 0.23 nM, which is lower than the maximum mercury contaminant level specified by the US Environmental Protection Agency. Good precision of analysis was obtained (3.1% relative standard deviation). Furthermore, the method was simple, involving in-situ mixing and sensing in a one-pot solution. Detection was accomplished in 5 min. This makes the method advantageous in terms of convenience and rapidity of analysis. The developed method was successfully applied for detection of Hg<sup>2+</sup> in tap water samples. Recoveries were found in range of 100.6–119.0%.
