Sriwatcharakul, Suttijit
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Preferred name
Sriwatcharakul, Suttijit
Alternative Name
Sriwatcharakul, S.
Main Affiliation
Email
suttijit.sr@kmitl.ac.th
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Item type:Publication, Evaluation of bioactivities of Delonix regia extracts from different regions of Thailand(2018-01-01)This research is to study bioactivity of Delonix regia flower and leaf extracts collected in Thailand. We analyzed for efficacy of free radical scavenging and found that flower and leaf extracts from Samut Prakan showed the strongest percentage of reduction with IC50 50.21 and 105.0 mg/ml, respectively. The result of evaluated phytochemicals revealed that Chon Buri's flower extract had the highest of total phenolic and tannin contents at 200 mg GAE/g extract and 32 mg TAE/g extract, respectively. Furthermore, Samut Prakan's flower extract had the highest flavonoid compounds at 328.5 mg QE/g extract. To examine cytotoxicity on breast cancer cell lines, we found that Samut Prakan's flower extract had the most cytotoxicity CC50 value, 5000 µg/ml. In conclusion, we found that the flower of Delonix regia is the promising part for the further study because the antioxidant activity and cytotoxicity strongly enhances when flower extract concentration is increased. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, INVESTIGATION OF BIOACTIVITIES FROM CASSIA FISTULA LINN. EXTRACTS(2025-01-01)This study explores the bioactivities of Cassia fistula Linn. (commonly known as the golden shower tree) by comparing the antioxidant, antibacterial, and cytotoxic properties of pod and seed ethanol extracts collected from Chonburi and Samut Prakan provinces in Thailand. The antioxidant potential was assessed through DPPH radical scavenging assay, where pod extracts exhibited higher activity than seed extracts, with IC₅₀ values of 0.98 and 1.09 mg/ml, respectively. The total phenolic content was highest in seed extracts from Samut Prakan (205.00 mg GAE/g extract), followed closely by pod extracts from Chonburi (167.50 mg GAE/g extract). Antibacterial screening via agar disc diffusion method showed that all extracts had significant inhibitory activity against gram positive; Bacillus subtilis and Micrococcus luteus. Samut Prakan pod extract inhibit M. luteus better than gentamicin. Cytotoxicity tests against MCF-7 breast carcinoma cells indicated that all extracts were non-toxic, and some even promoted cell viability, suggesting safety for potential therapeutic applications. These findings suggest that Cassia fistula, particularly its pod extracts, is a promising natural source candidate for future development in health-related applications.