Now showing 1 - 10 of 57
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Local and global stability analysis of dengue disease with vaccination and optimal control
    (2021-10-01)
    Chamnan, Anusit
    ;
    ;
    Tang, I. Ming
    ;
    Dengue fever is a disease that has spread all over the world, including Thailand. Dengue is caused by a virus and there are four distinct serotypes of the virus that cause dengue DENV‐1, DENV‐2, DENV‐3, and DENV‐4. The dengue viruses are transmitted by two species of the Aedes mosquitoes, the Aedes aegypti, and the Aedes albopictus. Currently, the dengue vaccine used in Thailand is chimeric yellow tetravalent dengue (CYD‐TDV). This research presents optimal control which studies the vaccination only in individuals with a documented past dengue infection (seropositive), regardless of the serotypes of infection causing the initial infection by the disease. The analysis of dengue transmission model is used to establish the local asymptotically stabilities. The property of symmetry in the Lyapunov function an import role in achieving this global asymptotically stabilities. The optimal control systems are shown in numerical solutions and conclusions. The result shows that the control resulted in a significant reduction in the number of infected humans and infected vectors.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    A model for the testosterone regulation taking into account the presence of two types of testosterone hormones
    (2015-06-01)
    Tanutpanit, T.
    ;
    ;
    Tang, I. M.
    The purpose of this paper is to study the effect of sex hormone binding globulin (SHBG) on the mathematical model of the hypothalamic-pituitary-gonadal (HPG) endocrine cycle which regulates the production of the male hormone testosterone. Large amounts of total circulating testosterone are bound to SHBG making them. Standard analytical techniques are used to analyze the modified mathematical model which includes a delay to account for the time required for luteinizing hormone emitted by the pituitary gland to reach the testis, to determine the steady state, its stability and the critical delay needed for the bifurcation. Numerical simulation of the solutions of the model is performed to illustrate the possible behaviors.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    A modified optimal control for the mathematical model of dengue virus with vaccination
    (2023-01-01)
    Pongsumpun, Puntipa
    ;
    Lamwong, Jiraporn
    ;
    Tang, I. Ming
    ;
    The dengue viruses (of which there are four strains) are the causes of three illnesses of increasing severity; dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Recently, dengue fever has reached epidemic proportion in several countries. Strategies or preventative methods have to be developed to combat these epidemics. This can be done by development of vaccines or by preventing the transmission of the virus. The latter approach could involve the use of mosquito nets or insecticide spraying. To determine which strategy would work, we test the strategy using mathematical modeling to simulate the effects of the strategy on the dynamics of the transmission. We have chosen the Susceptible-Exposed-Infected-Recovered (SEIR) model and the Susceptible, Exposed-Infected (SEI) model to describe the human and mosquito populations, repectively. We use the Pontryagin’s maximum principle to find the optimal control conditions. A sensitivity analysis revealed that the transmission rate (ɣ<inf>ℎ</inf>, ɣ<inf>v</inf>), the birth rate of human population (µ<inf>ℎ</inf>), the constant recruitment rate of the vector population (A) and the total human population (N<inf>ℎ</inf>) are the most influential factors affecting the disease transmission. Numerical simulations show that the optimal controlled infective responses, when implemented, cause the convergence to zero to be faster than that in uncontrolled cases.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    The dynamical model of dengue vertical transmission
    (2017-01-01)
    Dengue disease is usually found in many parts of the world, including Africa, Asia, South America and Australia. Dengue disease can pass from one individual to another by two distinct mechanisms such as horizontal transmission and vertical transmission. In horizontal transmission, susceptible individuals can be infected by direct or indirect contacts with infectious individuals who are stays at the same time. Vertical transmission means to direct transmission from infected parents to their offspring before or during birth. In this study, the dynamical model of dengue disease was formulated by considering the vertical transmission in Aedes mosquitoes. The analysis of our model was given. The results of this study should introduce the alternative ways to reduce the dengue outbreak.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Transmission model of dengue virus by Aedes aegypti and Aedes albopictus
    (2013-12-01)
    Sungchasit, R.
    ;
    ;
    Tang, I. M.
    Mathematical models are used for describing many diseases. Dengue disease is occurred by biting of infected Aedes aegypti and Aedes albopictus mosquitoes. Dengue outbreak is found during the rainy season. Each Aedes mosquito has the different dengue outbreaks and they depend on the temperature and areas. The standard dynamical modeling method is used in this study. The SIR (susceptible-infectedrecovered) model is modified to describe the transmission of dengue virus by two species of vectors. The transmission of dengue virus is varied with time. The dynamical analysis method is used for analyzing this model. We confirm these results by using numerical results. © 2013 Pushpa Publishing House, Allahabad, India.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Fractional-order modeling of dengue dynamics: exploring reinfection mechanisms with the Atangana–Baleanu derivative
    (2025-08-01)
    Lamwong, Jiraporn
    ;
    Dengue fever poses ongoing public health challenges due to its complex reinfection dynamics and antibody-dependent enhancement (ADE). To address limitations in classical models, this study proposes a novel fractional-order model utilizing the Atangana–Baleanu–Caputo derivative to capture memory and non-local effects inherent in dengue transmission. The model explicitly incorporates reinfection mechanisms and stages of infection, offering a more accurate depiction of disease progression. The existence and uniqueness of solutions are established using fixed-point theory, and the global stability of equilibria is analyzed via Lyapunov methods. Model fitting with real-world data from Thailand in 2023 confirms predictive accuracy, while sensitivity analysis identifies the biting and mosquito mortality rates as critical parameters influencing the basic reproduction number. This framework enhances the realism of epidemic models and provides actionable insights for designing targeted public health interventions in dengue-endemic regions.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Mathematical model for the transmission of two plasmodium malaria
    (2011-03-01)
    Malaria is transmitted to the human by biting of infected Anopheles mosquitoes. This disease is a serious, acute and chronic relapsing infection to humans. Fever, nausea, vomiting, back pain, increased sweating anemia and splenomegaly (enlargement of the spleen) are the symptoms of the patients who infected with this disease. It is caused by the multiplication of protozoa parasite of the genus Plasmodium. Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae and Plasmodium ovale are the four types of Plasmodium malaria. A mathematical model for the transmission of Plasmodium Malaria is developed in which the human and vector population are divided into two classes, the susceptible and the infectious classes. In this paper, we formulate the dynamical model of Plasmodium falciparum and Plasmodium vivax malaria. The standard dynamical analysis is used for analyzing the behavior for the transmission of this disease. The Threshold condition is found and numerical results are shown to confirm the analytical results.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Fractional-order Modeling and Optimal Control of Dengue-Malaria Co-infection with Local and Advanced Treatment Strategies
    (2026-01-01)
    Pongsumpun, Puntipa
    ;
    Ud Din, Rahim
    ;
    Ullah, Atta
    ;
    Abstract: This study presents a novel fractional-order co-infection model describing the joint transmission dynamics of dengue and malaria using the generalized fractional derivative. The total human population is divided into eight epidemiological compartments that account for single infections, co-infection, treatment stages, and recovery. The proposed framework incorporates memory effects and nonlocal behavior, offering a more realistic representation of disease progression compared to classical integer-order models. Local and advanced treatment strategies are introduced based on infection severity, allowing targeted intervention for both mild and co-infected cases. The fundamental mathematical properties of the model, including positivity, boundedness, existence, and uniqueness of solutions, are rigorously established. The basic reproduction number is derived, and both local and global stability of the disease-free equilibrium are analyzed using suitable Lyapunov functions. A statistical sensitivity analysis is performed to identify key parameters influencing disease transmission. Furthermore, optimal control strategies are formulated to minimize co-infection prevalence while reducing treatment and implementation costs. Numerical simulations validate the theoretical findings and demonstrate that fractional-order dynamics provide deeper insights into long-term disease behavior. The results offer valuable guidance for policymakers in designing effective and cost-efficient strategies to control dengue and malaria co-infection. Graphic Abstract: (Figure presented.) The
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Stability and oscillations of time-delayed model for the testosterone regulation
    (2013-11-04)
    Tanutpanit, T.
    ;
    ;
    Tang, I. M.
    In this paper, we develop the mathematical model with a time delay to describe the feedback mechanisms concerning of cyclicity of the male hormonal balance on the influence of variations in the sex hormone-binding globulin (SHBG) concentration. We show that a Hopf bifurcation occurs when a time delay τ passes through a critical value. Numerical simulations are performed to illustrate the analytical results. Moreover, this model can explain the pulsatile secretion of hormones in male.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Levenberg-Marquardt neural network-based intelligent computation for the non-Newtonian polymer during forward roll coating
    (2023-11-01)
    Ali, Fateh
    ;
    Hou, Yanren
    ;
    Feng, Xinlong
    ;
    Zahid, M.
    ;
    Ali, Muhammad Usman
    Scientists and researchers widely recognize the effectiveness of artificial intelligence (AI)-based machine learning and intelligent computing solvers, demonstrating qualities such as resilience, robustness, stability, and rapid convergence. One particularly significant and rapidly growing field within AI is artificial neural networks. This research uses a supervised neural network model based on Levenberg-Marquardt backpropagation (LMB-SNNs) to examine the Sisko fluid model for the forward roll coating process (SFM-FRCP). A suitable transformation is applied to the partial differential equations based SFM-FRCP mathematical model, resulting in a set of nonlinear ordinary differential equations. The perturbation method has been used to find the analytical solutions for the velocity profile, pressure gradient, and pressure profile. A dataset for varying the pertinent parameters is generated, and the LMB-SNNs technique has been used to estimate the velocity profile, pressure gradient, and pressure profile behavior during FRCP for numerous scenarios. The numerical solution for SFM-FRCP in different scenarios, such as the validation, training, and testing procedures of LMB-SNNs, is carried out. Moreover, the state transition index, fitness outline, mean square error, histogram error, and regression presentation also endorse the strength and reliability of the solver LMB-SNNs for SFM-FRCP. The comparative analyses and performance studies through outputs of regression drawings, absolute error, and error histograms validate the effectiveness of the suggested solver LMB-SNNs. The method's precision is verified by the closest numerical outputs of both built and dataset values with similar levels 10 − 11 - 10 − 14 . Furthermore, it has been observed that as the non-Newtonian parameter increases, the fluid velocity decreases. The research work carried out in this paper is original and fills a gap in the existing research by showing the rheological properties of the Sisko fluid model and the implementation of the LMB-SNNs during the FRCP.