Rattanawong, Wanakorn

Loading...
Thumbnail Image
Preferred name
Rattanawong, Wanakorn
Alternative Name
Rattanawong, W.
Main Affiliation
Email
wanakorn.ra@kmitl.ac.th

Settings

Now showing 1 - 2 of 2
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    A case of successive development of possible acute necrotizing encephalopathy after COVID-19 pneumonia
    (2022-03-01)
    Hemachudha, Pasin
    ;
    Pongpitakmetha, Thanakit
    ;
    Rattanawong, Wanakorn
    ;
    Thanapornsungsuth, Poosanu
    ;
    Joyjinda, Yutthana
    COVID-19 infection often results in an excessive inflammatory response with a spectrum of neurological manifestations. Here, we describe an 81-year-old female with severe COVID-19 pneumonia and subsequent alteration of consciousness after high-dose intravenous dexamethasone and remdesivir. A non-contrast head computed tomography (CT) demonstrated bilateral hypodensities involving bilateral cerebellar hemispheres, thalami, cerebral peduncles and medial parieto-occipital areas. There was no improvement and repeat CT showed progression with findings suggestive of acute necrotizing encephalopathy. Interleukin-6 levels were initially normal; however, subsequent levels were found to be markedly elevated. Acute necrotizing encephalopathy associated with COVID-19 may occur in the setting of severe pneumonia and may represent an immune-mediated process involving inflammatory cytokines such as interleukin-6.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Understanding the genetics and neurology: an overview of adult neurogenetics
    (2025-08-01)
    Hemachudha, Pasin
    ;
    Anukoolwittaya, Prakit
    ;
    Pongpitakmetha, Thanakit
    ;
    Joyjinda, Yutthana
    ;
    Ruchisrisarod, Chanida
    Neurogenetics investigates the genetic basis of neurological disorders. It encompasses conditions ranging from neurodegenerative diseases with predominantly polygenic risk genes, such as Alzheimer's and Parkinson's, to monogenic diseases and repeated expansion disorders within movement and neuromuscular disorders, such as Friedreich ataxia and muscular dystrophies. Significant advances in recent years that have revolutionized our understanding of disease mechanisms and paved the way for personalized medicine approaches are due to the field of neurogenetics, with its intricate relationship both with clinical and genetic research. Therefore, all neurologists, even in resource-limited settings, are aware of the critical genetic basis; standard molecular diagnostic techniques such as next-generation sequencing, whole exome, and whole genome sequencing; and possible therapeutic modalities of their field. This review will also touch on elements of the neurogenetic clinic in tertiary care, ethical considerations, and insight into ongoing research that would help improve patient care and enhance clinical outcomes.