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Estrus synchronization using intravaginal medroxyprogesterone acetate (MAP), MAP plus Prostaglandin F 2α, Controlled Internal Drug Release (CIDR) or CIDR plus Prostaglandin F 2α in Saanen dairy goats in Thailand
Author(s)
Kajaysri, Jatuporn
Date Issued
January 1, 2012
Type
Article
Abstract
The objective of this study was to compare the efficiency of medroxyprogesterone acetate (MAP) in the form of impregnated intravaginal sponges with or without Prostaglandin F 2α (PGF 2α) and natural progesterone impregnated controlled internal drug release (CIDR) devices with or without PGF 2α in dairy Saanen goats in Thailand. Seventy-five Saanen does were divided into five equal groups. The sixty does in Groups 1 to 4 in Experiment 1 were assigned for estrus synchronization using the following intravaginal progestagen techniques: sponges impregnated with MAP in Group 1 (n=15), sponges with MAP and intramuscular injection of 125 g PGF 2α in Group 2 (n=15), progesterone CIDR devices in Group 3 (n=15) and progesterone CIDR devices and intramuscular injection of 125 g PGF 2α in Group 4 (n=15). Intravaginal progestagens were administered for 13 d and the PGF 2α was injected on day 13. Estrus responses of does in Groups 1 to 4 were detected from 12 to 60 hr after progestagen withdrawal. In the remaining 15 does of Experiment 2 in Group 5, estrus was synchronized by intravaginal progestagen with MAP for 13 d. Estrus responses of does in Group 5 were detected at 24 and 48 hr after progestagen withdrawal. After estrus synchronization, the estrus does in Groups 1 to 5 were artificially inseminated with frozen semen once within 48-50 hr after progestagen withdrawal. However, for does in estrus in Group 5, the vaginal mucous accumulations were flushed with saline solution before artificial insemination (AI). Pregnancy was detected by ultrasonography on day 60 after AI. The result of Experiment 1 was estrus responses in all does in Groups 1, 2 and 4 but in only 10 does in Group 3. The mean estrus onset times of Groups 1 and 2 were not significantly different (21.0 ± 1.2 and 21.5 ± 1.3 hr, respectively) but were significantly different from those of Groups 3 (18.5 ± 1.9 hours) and 4 (18.6 ± 2.0 hr) (P < 0.05). The mean estrus durations of Groups 1 to 4 were not significantly different. Pregnancy ultrasonography revealed no difference in the pregnancy rates among Groups 1 to 4. Experiment 2 resulted in estrus responses in all does in Group 5. Comparison of the pregnancy rates of Groups 1 and 5 showed that Group 5 had a trend of a higher pregnancy rate than Group 1. It can be concluded that the MAP treatment with or without PGF 2α had equal efficacy to the CIDR-with-PGF 2α treatment, and that the MAP treatment combined with vaginal mucous flushing could possibly increase the conception rate.
Citation
Kasetsart Journal Natural Science, 46(1), 71-79, 2012