Improving Stability of Nanoemulsion Containing Centella asiatica, Lycopersicon Esculentum Mil. And Moringa oleifera Lam. Extract

Abstract

Natural extracts are interesting because those have bioactive compounds which can be used as antioxidants in pharmacological cosmetics. However, bioactive compounds are unstable to environment. In the present study, formulation and stability of Centella asiatica, Lycopersicon Esculentum Mil. and Moringa oleifera Lam. was performed using high shear homogenization (HSH) technique. Virgin coconut oil was based of oil phase for emulsion. The optimum formulation of the nanoemulsion consisted of 80:10:10 of water, tween 80 and oil, respectively. 1 % of natural extract nanoemulsion was homogenized for 20 minutes at 4,000 rpm. and stored at 4 ºC, 25 ºC and 40 ºC for 7 days. Particles size and electrokinetic potential of emulsion extract was determined by dynamic light scattering method. Single-phase solution and droplet size was observed in the range of 100 to 500 nm. The droplet size and stability of emulsions depends on temperature and times storage, which this study would be approached to develop a natural product in cosmetic market.