Antibacterial and anti-tyrosinase activities of the methanolic extracts from leaves of Tectona grandis

Abstract

The antibacterial and anti-tyrosinase activities of methanolic extracts from fresh and fallen leaves of Tectona grandis (Teak) was studied. Fresh and fallen of teak leaves were collected from Thongphaphum and Phitsanulok silviculture research station. Antibacterial activity was determined by disc diffusion method with concentration at 500 µg/disc. Fresh and fallen of teak leaves extracts showed a good activity against Staphylococcus aureus and Staphylococcus epidermidis. In the other hand, fresh teak leaves inhibited growth of Propionibacterium acnes better than fallen teak leaves. The anti-tyrosinase activity was determined by Dopachrome method with concentration at 1500 µg/ml, inhibitory power of tyrosinase enzyme from fresh and fallen leaves extracts value were detected in the percentage between 35.45%-73.65%.