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A mathematical model for erythroid regulation

Author(s)
Kumnungkit, Kanchana
Tang, I. Ming
Date Issued
June 1, 2006
Type
Article
Abstract
A mathematical model connecting the dynamics of the essential components in this process; the erythrocytes (RBC), the hormone erythropoietin (EPO) and the oxygen is proposed. A time delay is included to simulate the dynamics of the maturation steps. A bifurcation analysis is performed to determine the ranges of parameter values. The effects of the time delay are seen in the simulated production of the erythrocytes as the delay time is increased past the critical value.
Citation
Wseas Transactions on Mathematics, 5(6), 701-705, 2006
Subjects

Critical delay time

Delay

Erythropoiesis

Hopf bifurcation

Metrics
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