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    Influenza transmission model by dynamical analysis and cellular automata
    (2020-09-30)
    The infection of the airways and lung called as influenza. The influenza cases occurred every year. We can find influenza cases around the world. Influenza is an acute respiratory disease. Symptoms of the disease include fever, headache, myalgia, sore throat and cough. Children who infected with influenza may be associated with gastrointestinal symptoms such as nausea, vomiting, and diarrhea. The influenza cases are found in children and adults. SEIR model (S = susceptible, E = exposed, I = infectious, R = recovered) is described for the transmission of influenza. We analyzed the model by using dynamical analysis and Cellular automata is done to see the spread of influenza. The effects of each parameters influence to the transmission of this disease are shown.
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    Local Stability of Influenza Virus with Vaccination
    (2020-05-15)
    Influenza virus is an infectious disease. This caused by influenza virus. The symptoms consist of high fever, runny nose, sore throat, muscle and joint pain. In this paper, we construct the mathematical model for the transmission of influenza virus.We separate the human into 2 groups such as group of persons who obtain the vaccination and group of persons who do not obtain the vaccination. Each group, we separated the persons intothe susceptible, exposed, infectious, quarantined and recovered groups. We analyzed the equilibrium point and find the local stability of them by using standard dynamical modeling method. The basic reproduction number of this mathematical model is found. We obtain the condition for the disease fee steady state and endemic disease state will be local stability. Numerical results of the model are shown.
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    Local and global stability analysis of dengue disease with vaccination and optimal control
    (2021-10-01)
    Chamnan, Anusit
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    Tang, I. Ming
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    Dengue fever is a disease that has spread all over the world, including Thailand. Dengue is caused by a virus and there are four distinct serotypes of the virus that cause dengue DENV‐1, DENV‐2, DENV‐3, and DENV‐4. The dengue viruses are transmitted by two species of the Aedes mosquitoes, the Aedes aegypti, and the Aedes albopictus. Currently, the dengue vaccine used in Thailand is chimeric yellow tetravalent dengue (CYD‐TDV). This research presents optimal control which studies the vaccination only in individuals with a documented past dengue infection (seropositive), regardless of the serotypes of infection causing the initial infection by the disease. The analysis of dengue transmission model is used to establish the local asymptotically stabilities. The property of symmetry in the Lyapunov function an import role in achieving this global asymptotically stabilities. The optimal control systems are shown in numerical solutions and conclusions. The result shows that the control resulted in a significant reduction in the number of infected humans and infected vectors.
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    A model for the testosterone regulation taking into account the presence of two types of testosterone hormones
    (2015-06-01)
    Tanutpanit, T.
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    Tang, I. M.
    The purpose of this paper is to study the effect of sex hormone binding globulin (SHBG) on the mathematical model of the hypothalamic-pituitary-gonadal (HPG) endocrine cycle which regulates the production of the male hormone testosterone. Large amounts of total circulating testosterone are bound to SHBG making them. Standard analytical techniques are used to analyze the modified mathematical model which includes a delay to account for the time required for luteinizing hormone emitted by the pituitary gland to reach the testis, to determine the steady state, its stability and the critical delay needed for the bifurcation. Numerical simulation of the solutions of the model is performed to illustrate the possible behaviors.
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    A modified optimal control for the mathematical model of dengue virus with vaccination
    (2023-01-01)
    Pongsumpun, Puntipa
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    Lamwong, Jiraporn
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    Tang, I. Ming
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    The dengue viruses (of which there are four strains) are the causes of three illnesses of increasing severity; dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Recently, dengue fever has reached epidemic proportion in several countries. Strategies or preventative methods have to be developed to combat these epidemics. This can be done by development of vaccines or by preventing the transmission of the virus. The latter approach could involve the use of mosquito nets or insecticide spraying. To determine which strategy would work, we test the strategy using mathematical modeling to simulate the effects of the strategy on the dynamics of the transmission. We have chosen the Susceptible-Exposed-Infected-Recovered (SEIR) model and the Susceptible, Exposed-Infected (SEI) model to describe the human and mosquito populations, repectively. We use the Pontryagin’s maximum principle to find the optimal control conditions. A sensitivity analysis revealed that the transmission rate (ɣ<inf>ℎ</inf>, ɣ<inf>v</inf>), the birth rate of human population (µ<inf>ℎ</inf>), the constant recruitment rate of the vector population (A) and the total human population (N<inf>ℎ</inf>) are the most influential factors affecting the disease transmission. Numerical simulations show that the optimal controlled infective responses, when implemented, cause the convergence to zero to be faster than that in uncontrolled cases.
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    The dynamical model of dengue vertical transmission
    (2017-01-01)
    Dengue disease is usually found in many parts of the world, including Africa, Asia, South America and Australia. Dengue disease can pass from one individual to another by two distinct mechanisms such as horizontal transmission and vertical transmission. In horizontal transmission, susceptible individuals can be infected by direct or indirect contacts with infectious individuals who are stays at the same time. Vertical transmission means to direct transmission from infected parents to their offspring before or during birth. In this study, the dynamical model of dengue disease was formulated by considering the vertical transmission in Aedes mosquitoes. The analysis of our model was given. The results of this study should introduce the alternative ways to reduce the dengue outbreak.
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    Analysis of the Mathematical Model of Covid-19 in Thailand
    (2021-08-20)
    The purpose of this research is to study the characteristics of the COVID-19 virus in Thailand. We formulate the mathematical model of COVID-19 virus. We separate the human populations into 6 groups. The infected human populations are separated into 2 classes such as infectious human population with no show symptom and infectious human population with symptoms. We study the behavior of the equilibrium points of the model. Determine the conditions for the local stability of the equilibrium points. Numerical results of mathematical models are presented. This will lead to a reduction in the mortality rate of patients in Thailand.
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    Local stability analysis of mathematical model of Tuberculosis disease in Thailand
    (2021-01-15)
    Tuberculosis (TB) is a contagious disease that is caused by Mycobacterium. It can be transmitted by air. When infected Tuberculosis speaks, coughs or sneezes. TB is present in the sputum droplets and rises into the air. Large aerosol particles often fall on the ground and dry out. The main symptom of tuberculosis is a chronic cough that lasts 2 weeks or more. Other symptoms may include loss of appetite, weight loss, fatigue, fever, chest pain, shortness of breath. This disease is transmitted between human. In this paper, we find the dynamical equations of this disease. We analyzed our mathematical model to find the equilibrium points of our mathematical model. Numerical solutions are analyzed to see the distribution of each group of population. The basic reproduction number of the disease is derived. The influence of each factor is analyzed.
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    Transmission model of dengue virus by Aedes aegypti and Aedes albopictus
    (2013-12-01)
    Sungchasit, R.
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    Tang, I. M.
    Mathematical models are used for describing many diseases. Dengue disease is occurred by biting of infected Aedes aegypti and Aedes albopictus mosquitoes. Dengue outbreak is found during the rainy season. Each Aedes mosquito has the different dengue outbreaks and they depend on the temperature and areas. The standard dynamical modeling method is used in this study. The SIR (susceptible-infectedrecovered) model is modified to describe the transmission of dengue virus by two species of vectors. The transmission of dengue virus is varied with time. The dynamical analysis method is used for analyzing this model. We confirm these results by using numerical results. © 2013 Pushpa Publishing House, Allahabad, India.
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    Fractional-order modeling of dengue dynamics: exploring reinfection mechanisms with the Atangana–Baleanu derivative
    (2025-08-01)
    Lamwong, Jiraporn
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    Dengue fever poses ongoing public health challenges due to its complex reinfection dynamics and antibody-dependent enhancement (ADE). To address limitations in classical models, this study proposes a novel fractional-order model utilizing the Atangana–Baleanu–Caputo derivative to capture memory and non-local effects inherent in dengue transmission. The model explicitly incorporates reinfection mechanisms and stages of infection, offering a more accurate depiction of disease progression. The existence and uniqueness of solutions are established using fixed-point theory, and the global stability of equilibria is analyzed via Lyapunov methods. Model fitting with real-world data from Thailand in 2023 confirms predictive accuracy, while sensitivity analysis identifies the biting and mosquito mortality rates as critical parameters influencing the basic reproduction number. This framework enhances the realism of epidemic models and provides actionable insights for designing targeted public health interventions in dengue-endemic regions.