Flow effect on lesion formation in RF cardiac catheter ablation

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dc.contributor.authorCao, Hong
dc.contributor.authorVorperian, Vicken R.
dc.contributor.authorTungjitkusolmun, Supan
dc.contributor.authorTsai, Jang Zern
dc.contributor.authorHaemmerich, Dieter
dc.contributor.authorChoy, Young Bin
dc.contributor.authorWebster, John G.
dc.date.accessioned2026-08-06T09:51:03Z
dc.date.available2026-08-06T09:51:03Z
dc.date.issued2001-04-23
dc.description.abstractThis study investigated the flow effect on the lesion formation during radio-frequency cardiac catheter ablation in temperature-controlled mode. The blood flow in heart chambers carries heat away from the endocardium by convection. This cooling effect requires more power from the ablation generator and causes a larger lesion. We set up a flow system to simulate the flow inside the heart chamber. We performed in vitro ablation on bovine myocardium with three different flow rates (0 L/min, 1 L/rain and 3 L/min) and two target temperatures (60 °C and 80 °C). During ablation, we also recorded the temperatures inside the myocardium with a three-thermocouple temperature probe. The results show that lesion dimensions (maximum depth, maximum width and lesion volume) are larger in high flow rates (p < 0.01). Also, the temperature recordings show that the tissue temperature rises faster and reaches a higher temperature under higher flow rate.
dc.identifier.citationIEEE Transactions on Biomedical Engineering, 48(4), 425-433, 2001
dc.identifier.doi10.1109/10.915708
dc.identifier.issn00189294
dc.identifier.other2-s2.0-0035066171
dc.identifier.urihttps://dspace.kmitl.ac.th/handle/123456789/404
dc.sourceIEEE Transactions on Biomedical Engineering
dc.subjectAblation
dc.subjectCardiac catheter ablation
dc.subjectConvection film coefficient
dc.subjectLesion dimension
dc.subjectRF cardiac catheter ablation
dc.subjectTemperature recording
dc.titleFlow effect on lesion formation in RF cardiac catheter ablation
dc.typeArticle

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