Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications

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dc.contributor.authorKorawinwich Boonpisuttinant
dc.contributor.authorThanachai Taka
dc.contributor.authorWarintorn Ruksiriwanich
dc.contributor.authorRomchat Chutoprapat
dc.contributor.authorSarinporn Udompong
dc.contributor.authorRattiya Kansawang
dc.contributor.authorJinapa Sangsee
dc.contributor.authorWirinda Chompoo
dc.contributor.authorKitrawi Samothai
dc.contributor.authorRatakorn Srisuttee
dc.date.accessioned2026-05-08T19:16:04Z
dc.date.issued2023-10-31
dc.description.abstractcells at 31.63 ± 0.70%. The GIG-S-B, GIG-S-M, and GIG-R-M extracts demonstrated the highest collagen biosynthesis, which was comparable to vitamin C (p < 0.05), whereas the GIG-R-B extracts gave the highest stimulation of anti-aging genes (SIRT1 and FOXO1). All extracts at the concentration of 0.1 mg/mL showed no cytotoxicity on human skin fibroblasts. Therefore, the GIG-S-B extract was discovered to be a promising natural anti-aging agent for dermatological health and aesthetic applications that can be further developed in cosmetic, functional food and food supplement industries.
dc.identifier.doi10.1038/s41598-023-45434-3
dc.identifier.urihttps://dspace.kmitl.ac.th/handle/123456789/15350
dc.publisherScientific Reports
dc.subjectPhytochemistry and Bioactivity Studies
dc.subjectBee Products Chemical Analysis
dc.subjectSkin Protection and Aging
dc.titleAssessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications
dc.typeArticle

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