New insights into the neuroprotective and beta-secretase1 inhibitor profiles of tirandamycin B isolated from a newly found Streptomyces composti sp. nov.

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dc.contributor.authorThitikorn Duangupama
dc.contributor.authorJaturong Pratuangdejkul
dc.contributor.authorSumet Chongruchiroj
dc.contributor.authorPattama Pittayakhajonwut
dc.contributor.authorChakapong Intaraudom
dc.contributor.authorSarin Tadtong
dc.contributor.authorPatcharawee Nunthanavanit
dc.contributor.authorWeerasak Samee
dc.contributor.authorYa‐Wen He
dc.contributor.authorSomboon Tanasupawat
dc.contributor.authorChitti Thawai
dc.date.accessioned2026-05-08T19:17:39Z
dc.date.issued2023-3-24
dc.description.abstractadministration models at 1 ng/mL, respectively, without neurotoxicity on murine P19-derived neuron cells nor cytotoxicity against Vero cells. This study was reportedly the first study to show the neuroprotective and BACE1 inhibitory activities of TAM B.
dc.identifier.doi10.1038/s41598-023-32043-3
dc.identifier.urihttps://dspace.kmitl.ac.th/handle/123456789/16118
dc.publisherScientific Reports
dc.subjectMicrobial Natural Products and Biosynthesis
dc.subjectGenomics and Phylogenetic Studies
dc.subjectChemical Synthesis and Analysis
dc.titleNew insights into the neuroprotective and beta-secretase1 inhibitor profiles of tirandamycin B isolated from a newly found Streptomyces composti sp. nov.
dc.typeArticle

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