DBU‐Mediated Reaction of 3‐Chlorooxindole and 9‐Xanthyl Fluorene for Synthesis of 3‐Arylidene Oxindole
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Asian Journal of Organic Chemistry
Abstract
Abstract This work reports a new route for the synthesis of 3‐(9 H ‐fluoren‐9‐ylidene)indolin‐2‐one derivatives via the reaction of 3‐chlorooxindoles and O ‐ethyl S ‐(9 H ‐fluoren‐9‐yl) carbonodithioates mediated by 1,8‐diazabicyclo[5.4.0]undec‐7‐ene (DBU). The reactions readily proceeded at room temperature, enable a collection of 3‐alkenyl oxindoles to be prepared within a short reaction time (15 minutes). The 3‐alkenyl oxindoles can be easily converted to 3‐fluorenyl oxindoles by NaBH 4 reduction.