Ensemble deep learning for the detection of COVID-19 in unbalanced chest X-ray dataset

dc.contributor.authorWin, Khin Yadanar
dc.contributor.authorManeerat, Noppadol
dc.contributor.authorSreng, Syna
dc.contributor.authorHamamoto, Kazuhiko
dc.date.accessioned2026-08-06T10:33:53Z
dc.date.available2026-08-06T10:33:53Z
dc.date.issued2021-11-01
dc.description.abstractThe ongoing COVID-19 pandemic has caused devastating effects on humanity worldwide. With practical advantages and wide accessibility, chest X-rays (CXRs) play vital roles in the diagnosis of COVID-19 and the evaluation of the extent of lung damages incurred by the virus. This study aimed to leverage deep-learning-based methods toward the automated classification of COVID-19 from normal and viral pneumonia on CXRs, and the identification of indicative regions of COVID-19 biomarkers. Initially, we preprocessed and segmented the lung regions usingDeepLabV3+ method, and subsequently cropped the lung regions. The cropped lung regions were used as inputs to several deep convolutional neural networks (CNNs) for the prediction of COVID-19. The dataset was highly unbalanced; the vast majority were normal images, with a small number of COVID-19 and pneumonia images. To remedy the unbalanced distribution and to avoid biased classification results, we applied five different approaches: (i) balancing the class using weighted loss; (ii) image augmentation to add more images to minority cases; (iii) the undersampling of majority classes; (iv) the oversampling of minority classes; and (v) a hybrid resampling approach of oversampling and undersampling. The best-performing methods from each approach were combined as the ensemble classifier using two voting strategies. Finally, we used the saliency map of CNNs to identify the indicative regions of COVID-19 biomarkers which are deemed useful for interpretability. The algorithms were evaluated using the largest publicly available COVID-19 dataset. An ensemble of the top five CNNs with image augmentation achieved the highest accuracy of 99.23% and area under curve (AUC) of 99.97%, surpassing the results of previous studies.
dc.identifier.citationApplied Sciences Switzerland, 11(22), 2021
dc.identifier.doi10.3390/app112210528
dc.identifier.issn20763417
dc.identifier.other2-s2.0-85119300906
dc.identifier.urihttps://dspace.kmitl.ac.th/handle/123456789/12372
dc.sourceApplied Sciences Switzerland
dc.subjectChest X-rays
dc.subjectCOVID-19
dc.subjectDeep learning
dc.subjectEnsemble learning
dc.subjectImage augmentation
dc.subjectOversampling
dc.subjectUndersampling
dc.subjectWeighted loss
dc.titleEnsemble deep learning for the detection of COVID-19 in unbalanced chest X-ray dataset
dc.typeArticle

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