Directed-evolution approach to empower EGFR targeting for immunotherapy
| dc.contributor.author | Bunyarit Meksiriporn | |
| dc.contributor.author | Jamie B. Spangler | |
| dc.date.accessioned | 2026-05-08T19:20:27Z | |
| dc.date.issued | 2024-4-1 | |
| dc.description.abstract | Advances in directed-evolution technologies are enabling new strategies to isolate binding proteins that recognize disease-associated states of a target protein. In this issue of Cell Reports Methods, Dobersberger et al. devised a yeast display-based selection scheme to discover proteins that engage the cancer-associated activated state of a receptor to enable design of safe and effective immunotherapies. | |
| dc.identifier.doi | 10.1016/j.crmeth.2024.100762 | |
| dc.identifier.uri | https://dspace.kmitl.ac.th/handle/123456789/17526 | |
| dc.publisher | Cell Reports Methods | |
| dc.subject | CAR-T cell therapy research | |
| dc.subject | Viral Infectious Diseases and Gene Expression in Insects | |
| dc.subject | Monoclonal and Polyclonal Antibodies Research | |
| dc.title | Directed-evolution approach to empower EGFR targeting for immunotherapy | |
| dc.type | Article |