Antitumor activities of carboplatin–doxorubicin–ZnO complexes in different human cancer cell lines (breast, cervix uteri, colon, liver and oral) under UV exposition

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dc.contributor.authorSuttirak Pairoj
dc.contributor.authorPattareeya Damrongsak
dc.contributor.authorBadin Damrongsak
dc.contributor.authorNatini Jinawath
dc.contributor.authorRossukon Kaewkhaw
dc.contributor.authorChinnapat Ruttanasirawit
dc.contributor.authorTanaporn Leelawattananon
dc.contributor.authorKitsakorn Locharoenrat
dc.date.accessioned2026-05-08T19:17:27Z
dc.date.issued2021-1-1
dc.description.abstractof 0.137 µg/mL, whereas the loading capacity and efficiency of CP-DOX-ZnO were 77.81% and 99.05%, respectively. Fluorescence images confirmed that CP-DOX-ZnO using DOX served as a fluorescence enhancer specifically bound onto the cell membranes, which became almost saturated after 24 h incubation. Carboplatin-DOX-ZnO was possibly endocytosed by cancer cells and was selectively internalized into the target cells; thus, free chemo drug was released in the cytoplasm, which induced acute apoptosis. This resulted in complete inhabitation of growth signal of target cancer cells.
dc.identifier.doi10.1080/21691401.2021.1876718
dc.identifier.urihttps://dspace.kmitl.ac.th/handle/123456789/15999
dc.publisherArtificial Cells Nanomedicine and Biotechnology
dc.subjectNanoplatforms for cancer theranostics
dc.subjectMetal complexes synthesis and properties
dc.subjectSynthesis and Characterization of Heterocyclic Compounds
dc.titleAntitumor activities of carboplatin–doxorubicin–ZnO complexes in different human cancer cell lines (breast, cervix uteri, colon, liver and oral) under UV exposition
dc.typeArticle

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