Optimal control of dengue transmission with vaccination

dc.contributor.authorChamnan, Anusit
dc.contributor.authorPongsumpun, Puntani
dc.contributor.authorTang, I. Ming
dc.contributor.authorWongvanich, Napasool
dc.date.accessioned2026-08-06T10:33:12Z
dc.date.available2026-08-06T10:33:12Z
dc.date.issued2021-08-01
dc.description.abstractDengue disease is caused by four serotypes of the dengue virus: DEN-1, DEN-2, DEN-3, and DEN-4. The chimeric yellow fever dengue tetravalent dengue vaccine (CYD-TDV) is a vaccine currently used in Thailand. This research investigates what the optimal control is when only individuals having documented past dengue infection history are vaccinated. This is the present practice in Thailand and is the latest recommendation of the WHO. The model used is the Susceptible-Infected-Recovered (SIR) model in series configuration for the human population and the Susceptible-Infected (SI) model for the vector population. Both dynamical models for the two populations were recast as optimal control problems with two optimal control parameters. The analysis showed that the equilibrium states were locally asymptotically stable. The numerical solution of the control systems and conclusions are presented.
dc.identifier.citationMathematics, 9(15), 2021
dc.identifier.doi10.3390/math9151833
dc.identifier.issn22277390
dc.identifier.other2-s2.0-85112397573
dc.identifier.urihttps://dspace.kmitl.ac.th/handle/123456789/12199
dc.sourceMathematics
dc.subjectDengue disease
dc.subjectOptimal control
dc.subjectVaccination
dc.titleOptimal control of dengue transmission with vaccination
dc.typeArticle

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