The new quinazoline derivative (N-methyl-N-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats - Usana Chatturong; Krongkarn Chootip; Hélène Martin; Maude Tournier-Nappey; Kornkanok Ingkaninan; Prapapan Temkitthawon; Saharat Sermsenaphorn; Thanachon Somarin; Adchatawut Konsue; M. Paul Gleeson; Perle Totoson; Céline Demougeot (European Journal of Pharmacology, 2023)
Keywords: Phosphodiesterase function and regulation; Renin-Angiotensin System Studies; Nitric Oxide and Endothelin Effects