Srisang, Siriwan
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Srisang, Siriwan
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Email
siriwan.sr@kmitl.ac.th
18 results
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Item type:Publication, Rapid and accurate classification of Aspergillus ochraceous contamination in Robusta green coffee bean through near-infrared spectral analysis using machine learning(2023-03-01) ;Ruttanadech, Nuttapong; ; ; Near-infrared (NIR) spectral-based classification of Aspergillus ochraceous contamination in the Robusta green coffee bean was investigated. Six different learning algorithms, including linear discriminant analysis (LDA), support vector machine (SVM), k-nearest neighbors (KNN), decision tree (Tree), Naive Bayes (NB), and quadratic discriminant analysis (QDA), were applied for the investigating purpose. Four classes of fungal contamination on coffee beans, non-fungal contaminated beans on day 1 and day 3 (NCB-D1 and NCB-D3) and fungal contaminated beans on day 1 and day 3 (CB-D1 and CB-D3), were set for the classification intention. Based on the 6 learning algorithms, the Tree approach was optimal, displaying a training accuracy of 97.5%. As proven by the testing dataset, the classification accuracy of the Tree was also at 97.5%. With this number, the Tree could correctly classify 100% between the contaminated and non-contaminated coffee beans. These findings exhibit the potential of the NIR spectroscopy accompanied by machine learning for the early detection of fungal contamination in green coffee beans. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Dip- and Spray-coating of Schanz pin with PLA and PLA nanosphere for prolonged antibacterial activity(2021-10-01) ;Chinavinijkul, Panarin ;Riansuwan, Kongkhet ;Kiratisin, Pattarachai; Nasongkla, NorasedIn this study, variation of coating parameters was performed to determine a suitable condition for a vancomycin-coated Schanz pins in poly(lactic acid) (PLA) for prolonged antibacterial activity. Herein, the solvent used to dissolve the polymer (DCM vs. CHCl<inf>3</inf>), the concentration of the polymer in the solvent (2 vs. 5% w/v), the vertical withdrawing speed of the implant from the solution (0.4 vs. 2.4 cm/s), and the number of dip-coating cycles denoted in layers (1 L vs. 3 L) were investigated for its drug loading. Results showed that the optimal parameters were at 2% w/v PLA in DCM at 0.4 cm/s withdrawing speed and at 3 cycles for a high vancomycin loading with low deviation in result. Another experiment was performed by varying the concentration (1, 2, 4% w/v) and number of dip-coating cycles (10 L, 20 L, 30 L) which finalized 2% w/v PLA at 10 cycles as the optimal drug loading at 2.04 ± 0.09 mg. When observing the drug-release profile, the prior formulation released 2.21 ± 0.01 mg or 92.88 ± 0.44% of drug in one week. To reduce the amount of drug release in the first week, the method was further improved by spray-coating with PLA nanospheres (PLA-NS) for multiple cycles (10-, 20-, and 30-NS) to prolong drug release. After one, two, and three weeks, the drug-release were around 76%, 80%, and 88%, respectively. However, more drugs were lost as the number of cycles increases which suggests that lower (10-NS) coating cycle is better. Therefore, the final process was selected to be 2% PLA dip-coated for 10 cycles then spray-coated with PLA nanosphere for 10 cycles. Results showed that this method can help prolong release for at least 24 days. A short-term bacterial and cytotoxicity tests were done for 3 days with no S.aureus formed nor cytotoxicity. These results supported that the coating was successful in inhibiting the growth of S.aureus. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, In silico investigation of ACE2 and the main protease of SARS-CoV-2 with phytochemicals from Myristica fragrans (Houtt.) for the discovery of a novel COVID-19 drug(2022-09-01) ;Ongtanasup, Tassanee ;Wanmasae, Smith; ;Manaspon, ChawanNet-anong, SoiphetSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), is a new coronavirus strain that was first reported in December 2019 in Wuhan, China. A specific treatment for COVID-19 has yet to be identified. Potential therapeutic targets include SARS-CoV-2 main protease (Mpro) and the SARS-CoV-2 spike-ACE2 interaction. Molecular docking, molecular dynamics (MD), solvent screening for the extraction of the specified compounds, and prediction of the drug properties of certain molecules were the methods used in this study to investigate compounds from the medicinal plant Myristica fragrans, which is one of twelve herbs in Prasachandaeng remedy (PSD). ArgusLab, AutoDock Vina, and AutoDock were used to perform docking tasks. The examined ligands were compared with panduratin A as a standard (Kanjanasirirat et al., 2020), which is a promising medicinal plant molecule for the treatment of COVID-19. Molecular docking revealed that malabaricones B and C and licarins A, B and C bound to SARS-CoV-2/ACE2 and SARS-CoV-2 Mpro with low binding energies compared to that of the standard ligand. Furthermore, appropriate solvent usage is important. Acetone was selected by COSMOquick software for compound extraction in this investigation because it can extract large amounts of all five of the abovementioned M. fragrans compounds. Furthermore, the drug-like properties of these compounds were studied utilizing the Lipinski, Veber, and Ghose criteria. The results revealed that these M. fragrans compounds have potential as effective medicines to combat the COVID-19 pandemic. However, to assess the therapeutic potential of these ligands, additional research is needed, which will use our findings as a foundation. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clay tiles production using palm ash, spent bleaching earth, and palm fiber as substitute materials(2020-01-01); The objective of this research was to study the clay tile (CT) production using palm ash (PA), spent bleaching earth (SBE) and palm fiber (PF) as substitute materials. The effect of ingredients and PF length on CT qualities were investigated. The ingredient of clay: PA: SBE: PF used three proportions as following 58: 20: 20: 2, 56: 20: 20: 4, and 54: 20: 20: 6 (% by weight, wt). Each ingredient used the fiber length of 15 and 25 mm. The crystalline phase of raw materials was inspected. The CT after production were examined qualities as accorded with Thai industrial standard (TIS) in terms of water absorption, bulk density, acid corrosion and transverse breaking strength (TBS). Results showed that the clay tile qualities in terms of bulk density and acid corrosion were in the acceptable level as 1.45-1.65 g/cm<sup>3</sup> and less than 0.03%, respectively. The water absorption quality was more than 6.5% and the TBS was below 600 N. Hence, this research also revealed that the all wastes (PA, SBE, PF) from palm oil industry can be used to produce the clay tile. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Enhanced biodiesel purification using coffee husk bioadsorbents: The role of pyrolysis temperature, KOH activation, and adsorption efficiency(2025-05-01); ; ; ; Ruttanadech, NuttapongThis study evaluates the performance of bioadsorbents derived from coffee husk pyrolyzed at temperatures of 600, 700, and 800 °C (CH600, CH700, and CH800), along with activated CH700 (ACH700), in biodiesel purification. The results indicate that CH700 significantly enhances biodiesel purity, with optimal purification conditions achieved at a dosage of 2 wt% CH700, a stirring rate of 400 rpm, and a contact time of 45 min. CH700 demonstrated modest performance, achieving approximately 20 % removal of methanol and water. However, after activation with potassium hydroxide (KOH), ACH700 demonstrated improved efficiency, achieving 96.92 % methanol removal and 39.46 % water removal. ACH700 also refined biodiesel quality to meet EN14214 standards and maintained a higher biodiesel yield compared to other adsorbents. The bioadsorption process is influenced by the chemical interactions between the surface functional groups of the bioadsorbent and the contaminants, which is further enhanced by the optimized pore structure of ACH700. The use of ACH700 represents a novel and highly effective approach to biodiesel purification, combining both technical efficiency and economic feasibility. Furthermore, the valorization of agricultural waste adds significant environmental benefits, reinforcing the potential of ACH700 for large-scale biodiesel production. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Production of Biomass Briquette from Residual Bleaching Earth and Empty Palm Bunch(2017-01-01); ; ;Wongpitithawat, Pitiwat ;The-Eye, KorawitWongkeaw, KittipongBleaching earth (BE) and empty palm bunches (EPB) are residual materials in the palm oil production process. Inside BE consisted of copious oil quantities, in the same way, the EPB had the high heating value. These residual materials could be recycled to become the biomass briquettes (BB). Therefore, this work investigated the BB production at the different condition. The compression temperature was 150, 250 and 350°C. The compressive velocity was 30, 40 and 50 rpm. The mixture ratio by weight between BE and EPB was 30:70, 40:60, 50:50, 60:40 and 70:30. After production, the BB were examined the fuel properties, i.e., moisture content (MC), ash content (AC), the heating value (HV), the fixed carbon content (FC) and volatile matter content (VC). Experimental results showed the MC, HV, FC and VC diminished with the decrease of EPB quantity. The AC increased with the augmentation of BE content. The BB production rate increased with the compression velocity by it had the maximum production rate about 390 pieces per hour at the velocity of 50 rpm. Moreover, the increased velocity affected the diminution of HV, fixed carbon, moisture and volatile matter for some the mixture ratio and compression temperature. The alteration of compression temperature insignificantly affected the quantity of HV for some the mixture ratio and compression velocity. The BB production should be produced at the ratio of 30:70 combined with the compressive speed and temperature of 30 rpm and 250°C, respectively. This condition gave the high HV, the low moisture content corresponded with the standard of fuel properties, excepting, the quantity of ash and fixed carbon. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Fabrication of Eco-Friendly Pineapple Leaf Fiber-Based Vegan Leather for Environmental Sustainability(2026-01-20); ; ; ;Eiangmee, OrranatMaikaew, JatuphatThe environmental impact of synthetic leather production has raised global concerns due to its reliance on petroleum-based polymers and poor biodegradability. Therefore, the development of sustainable, eco-friendly alternatives using renewable resources has become increasingly important. A biodegradable vegan leather was developed from natural rubber and pineapple leaf fibers (PALF), with properties analyzed using Response Surface Methodology (RSM). The effects of fiber content (X1), compression time (X2), and compression temperature (X3) were studied on biodegradation (Y1), water absorption (Y2), and tensile strength (Y3). Results showed that all three factors significantly influenced Y1, with the predictive model demonstrating high reliability (R > 90%). The optimum condition for Y1 was X1 = 3.0 g, X2 = 70.0 min, and X3 = 110.0 C, yielding a maximum predicted biodegradation of about 21%. In contrast, the models for Y2 and Y3 were statistically unreliable (P > 0.05) due to low R² values. However, Y2 passed the lack-of-fit test, suggesting an adequate model form, while Y3 failed (P < 0.05), indicating an inadequate prediction model. These findings suggest future experiments should narrow factor ranges and include additional control variables to improve the predictability of Y2 and Y3. Despite these limitations, the study highlights a sustainable alternative to conventional synthetic leather, aligning with circular economy principles and supporting the United Nations Sustainable Development Goals (SDGs). Importantly, the process is resource-efficient: from 1 kg of pineapple leaves, only 20 g of fibers is obtained, and just 75 g of PALF was used in 15 experimental runs. This minimal material requirement underscores the potential of the approach for sustainable production, while highlighting potential applications in sustainable fashion, packaging, and eco-friendly product design. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Layer-by-layer dip coating of Foley urinary catheters by chlorhexidine-loaded micelles(2019-02-01); Nasongkla, NorasedChlorhexidine-loaded poly(ethylene glycol)-block-poly(ε-caprolactone) micelles (CHX-micelles) were prepared by the solvent evaporation method and were used to coat urinary catheters. The layer-by-layer (LbL) dip coating technique was used to coat the micelles onto the catheters, which consisted of the alternation of coating with CHX-micelles and poly(acrylic acid). The number of LbL nanocoating cycles was varied, and the properties of the coated catheters were investigated for their drug content and the coating thickness. The optimal coated catheter had 90 bilayers, which provided the maximum CHX content at 32.3 ± 1.4 μg/cm<sup>2</sup>, and the thickness of the thin film on these coated catheters was 6.87 ± 0.36 μm. Coated catheters were studied in the in vitro CHX-release, antibacterial activity, cytotoxicity, and hemolytic activity. Drug release from the coated catheters was controlled, and bacteria proliferation was inhibited for up to 6 days. Results suggest that the antimicrobial activity of the coated catheter reduces the adherence of uropathogens to the catheter's surface. The cytotoxicity and hemolytic activity of the coated catheters showed biocompatible properties. The coated catheter presented the potential to inhibit uropathogen colonization and formation. This nanocoating technology can also be applied to other medical implants that carry the risk of infection. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Recycling spent bleaching earth and oil palm ash to tile production: Impact on properties, utilization, and microstructure(2021-04-20); Spent bleaching earth (SBE) and oil palm ash (PA) were recycled to utilize as substitute material for producing tile. The proper quantity of SBE and PA in three clay groups (40, 60, and 80% by weight) was explored combined with varying compression pressure (90, 100 and 110 bar) and firing temperature (1000 and 1100 °C). All conditions were analyzed the influence and interaction of producing factors, i.e. mixture (M), compression pressure (C), and firing temperature (F) on tile attributes. Tile utilizations (water absorption, strength, acid resistance, color and leaching heavy metal) and cost were compared with the commercial tile. The microstructures were also examined. Results found that the mixture B at high clay group provided low water absorption ≈ 5–6%, moderate TBL ≈620–630 N, low corrosion ≈0.015–0.026%, and there were cheaper cost and better utilizations than commercial tile. Mixture B detected enough quartz and mullite which provided more strength. Hence, the SBE and OPA can be utilized for tile production with the tile properties agreed with industrial standard. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, An innovative chitosan-coated aquatic feed pellets production from coastal waste using top-spray fluidized bed drying(2026-12-01) ;Maikaew, Jatuphat; ;Tambunlertchai, SupreedaCoastal wastes such as crab shells, shrimp shells, and seaweed are rich in proteins, lipids, and bioactive compounds, making them valuable raw materials for aquafeed production. In this work, three aquatic feed pellets were developed and tested under different drying temperatures from 70 to 110 °C to evaluate the pellet durability index (PDI), specific energy consumption in water removal (SEW), and nutrient quality. The formulation containing high crab shell content showed the most balanced nutritional profile but required further improvement in mechanical strength. To address this, chitosan coating was applied using a top-spray fluidized bed system, with process conditions optimized through response surface methodology (RSM). The RSM demonstrated the optimal coating condition at a concentration of about 1.25% (w/v), a spray rate of about 32.5 mL/min, and a temperature of about 110 °C, with the lowest of drying time (DT) and specific energy consumption (SEC). The optimized coating significantly improved PDI and water solubility index while preserving nutritional balance. It also enhanced antimicrobial properties, which are desirable for feed storage. Microscopic and structural analyses confirmed good adhesion of the coating. Overall, this study demonstrates a sustainable pathway to convert coastal waste into high-quality aquafeed, offering both environmental benefits and practical value for aquaculture industries.
