Prachayawarakorn, Jutarat

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Preferred name
Prachayawarakorn, Jutarat
Alternative Name
Prachayawarakorn, J.
Main Affiliation
Email
jutarat.si@kmitl.ac.th

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    Item type:Publication,
    Natural wound dressing from acid-modified basil seed mucilage containing aloe vera extract
    (2024-01-01)
    Seeharaj, Panpailin
    ;
    Siriwat, Piyapol
    ;
    Phonrat, Arnon
    ;
    Prachayawarakorn, Jutarat
    There have been several studies that have applied basil)Ocimum basilicum L.(seed mucilage)BSM(as a wound dressing materials using several types of synthetic antimicrobial agents. This research reports on the application of BSM as a green wound dressing using natural substance, namely aloe vera (AV) extract for the improvement of antibacterial activity. Due to poor dimensional stability of BSM, malonic acid (MA) was used to crosslink the BSM molecules. The MA resulted in the esterification reaction between BSM molecules, as revealed by FTIR peak position of the C=O stretching. The porosity, water retention and swelling of BSM sponges were noted to decrease, while stiffness increased upon crosslinking. Incorporation of AV extract into both BSM and MA-crosslinked BSM sponges did not affect hydrophilicity, mechanical properties, thermal properties and cytotoxicity toward HaCaT cells. On the other hand, antibacterial activities against both Gram-positive bacteria)Staphylococcus aureus(and Gram-negative bacteria)Pseudomonas aeruginosa(of BSM and BSM crosslinked by MA were observed upon the addition of the AV extract.
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    Alternative Polysaccharide Wound Dressing from Heat-Moisture Starch/Basil Seed (O. Basilicum L.) Mucilage with Incorporated Glycolic Acid Antimicrobial Agent
    (2025-01-01)
    Phonrat, Arnon
    ;
    Subyai, Natkitta
    ;
    Prachayawarakorn, Jutarat
    In order to improve the behavior in water and the mechanical properties of heat-moisture treated starch, natural basil seed mucilage with high hydrophilicity and crystallinity was incorporated for wound dressing application. In addition, succinic acid cross-linking was used to enhance the durability of the material in water and glycolic acid was utilized as an antimicrobial agent. The effectiveness of the cross-linking process could be observed from the significant increase in dimensional stability from higher gel fraction value and increment of mechanical properties. Furthermore, the incorporation of glycolic acid into the wound dressing films demonstrated antibacterial efficacy, resulting in 100% bacterial reduction against S. aureus and E. coli strains. These films exhibited low cytotoxicity toward human epidermal keratinocytes (HaCaT) cells, indicating their potential for biomedical applications. Moreover, functional group analysis, crystallinity, morphology, thermal properties, gel fraction, water vapor transmission rate, free swell absorption, and mechanical properties were also examined.