Suteewong, Teeraporn
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Suteewong, Teeraporn
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teeraporn.su@kmitl.ac.th
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Item type:Publication, A concise review on design and control of structured natural rubber latex particles as engineering nanocomposites(2021-10-05) ;Wichaita, Waraporn ;Promlok, Duangkamol ;Sudjaipraparat, Narissara ;Sripraphot, SupangIn this article, we review the modification of natural rubber (NR) latex into the engineered particles for make use of them in functional nanocomposites. The review focuses on tuning nano-/microstructure and/or composition of NR latex particles by means of surface chemical functionalization, structural modification and incorporation of inorganic nanoparticles (NPs). Due to their polydispersity in size and non-spherical shape with complicated indigenous stabilizers, i.e., proteins and lipids, we first describe the fundamental and common methods for the modification of synthetic polymer latex which become a practical guideline for engineering of NR particles to a variety of designs. Subsequently, the examples of successfully modified NR latex and the involved parameters in the preparation are discussed. The different nature and properties of the modified NR latex compared to the synthetic latex are then depicted. Finally, specific examples of these systems used in a range of applications including nanofillers, controlled releasing materials, textiles, electronics and coatings are demonstrated. The research on modification of NR latex particles would be beneficial to the field of materials science and engineering for the valorization of naturally abundant colloidal polymer to the advanced functional materials in the broader utilization/commercialization in the future. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Controlled reversible assembly of gold nanoparticles as a new colorimetric and sensitive detection of glucose-6-phosphate dehydrogenase deficiency(2020-07-25) ;Boonyuen, Usa ;Praoparotai, Aun ;Chamchoy, Kamonwan ;Swangsri, ThitiluckWarakulwit, ChompunuchRecently, several studies have examined possible applications of nanoparticles for the development of electronic and optical sensors. The plasmon absorbance of gold nanoparticles has been used extensively to study biomolecular processes, including nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate-dependent enzymatic reactions. In this report, we describe the development of gold nanoparticles as a new colorimetric and sensitive detection method of glucose-6-phosphate dehydrogenase deficiency by means of controlled reversible assembly of gold nanoparticles. 3-nm polyvinylpyrrolidone/N,N′-dimethylaminopyridine-stabilized gold nanoparticles were synthesized, characterized and applied for an in vitro activity assay of 11 recombinant human glucose-6-phosphate dehydrogenase variants. Differences in the activity of the glucose-6-phosphate dehydrogenase variants from different deficiency classes were readily detected using the synthesized gold nanoparticles. The developed method can be easily distinguished with color change by naked eye for the detection of glucose-6-phosphate dehydrogenase deficiency. Moreover, we are the first to propose the segregation mechanism of polyvinylpyrrolidone/N,N′-dimethylaminopyridine-stabilized gold nanoparticles by reduced nicotinamide adenine dinucleotide phosphate. The method enables visual detection of glucose-6-phosphate dehydrogenase deficiency, which could be further developed for diagnostic testing of glucose-6-phosphate dehydrogenase deficiency. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Parameters Governing Void Formation and Expansion of Hollow Natural Rubber Latex Particles for Their Use as Bio-based Nanocapsules(2025-02-01) ;Promlok, Duangkamol; ;Polpanich, DuangpornTangboriboonrat, PramuanThis work reports the hollow latex (HL) particles developed from natural rubber latex particles (NRPs), known for their broad size distribution and non-spherical shape. HL-NRPs, prepared via the seeded emulsion polymerization in one pot, are studied as potential bio-based nanocapsules for the first time. Effects of types of crosslinking agents and swelling agents, the addition of sodium dodecyl sulfate (SDS), and monomer compositions on the void formation and expansion are systematically investigated. The combined effects of phase separation between NR core swelled with divinyl benzene (DVB) and hydrophilic poly(methyl methacrylate/acrylic acid) P(MMA/AA) shell, the entanglement of rubber chains copolymerized with MMA/DVB/AA monomers, and the osmosis from external aqueous medium promoted the void formation. While crosslinking agents affected the void formation and shell strength, SDS and type of monomers governed colloidal stability and polymerization loci as well as morphology, respectively. The ability of HL-NRPs as nanocapsules is explored by encapsulating fluorescent dyes, i.e., hydrophilic fluorescein isothiocyanate (FITC) and lipophilic Nile red (NiR), as model cargo. From the dye release test after 24 h, the cumulative concentrations of FITC in methanol and of NiR in tetrahydrofuran are 0.17 and 0.11 µg mL<sup>−1</sup>, respectively. The results suggested that FITC is released from HL-NRPs easier than NiR possibly due to the different encapsulation location. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Fabrication of hollow magnetic polyaniline particles via in-situ polymerization in one-pot for UV–Vis-NIR and EMI applications(2024-01-01) ;Promlok, Duangkamol ;Wichaita, Waraporn ;Phongtamrug, Suttinun ;Kaewsaneha, ChariyaSreearunothai, PaiboonThe concern on the adverse impacts of electromagnetic (EM) pollution has continuously increased. Instead of using heavy metal sheet, this work aims to develop magnetic polymeric particles, that can easily be incorporated in coatings, for EM/ultraviolet-visible-near infrared (UV–Vis-NIR) shielding. By carefully design structure and key components, hollow magnetic (HoM) polyaniline (PANI) particles possessing a void encircled with magnetic nanoparticles dispersed in PANI semi-conductive shell were fabricated via the oxidative polymerization in emulsion system. By using ethyl benzene as a soft template and different surfactive dopants, i.e., sodium dodecyl sulfate, sodium dodecylbenzene sulfonate, and poly(sodium 4-styrenesulfonate) (PSS), the HoM-PANI particles (0.5–2 μm) with well-defined hollow structure, high magnetic loading (17–21%wt), and superparamagnetic properties were obtained. The particle size distribution, and magnetic loading were slightly affected by the reaction temperature, whereas molecular weight (M<inf>w</inf>) of the localized dopant considerably influenced on the levels of interparticle connectivity, and hence, the conductivity could be tailored. The water dispersible HoM-PANI particles could form opaque coating, and free-standing film. PSS with M<inf>w</inf> of 70 K and 1 M yielded the larger HoM-PANI particles and more opaque films than small dopant molecules. Void size was the determining effect on excellent opacity of the coating containing HoM-PANI dispersed in poly(vinyl alcohol) matrix against UV–Vis-NIR, and EM radiation. The ability to tune their optical properties, and electrical conductivity accomplished by designing the particle nanostructure, and doping/de-doping by localized dopants enables them the promising candidates for functional paint, and film for irradiation protection. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A Predictive Dual-Stage Neural Framework for Phase-Coherent Auditory Synthesis on Edge Devices(2026-06-01) ;Pairoch, Sathit; Real-time binaural beat synthesis in dynamic acoustic environments is challenged by carrier non-stationarity, interaural phase discontinuities, and processing delay in conventional digital signal processing pipelines. This study proposes a predictive dual-stage neural framework for phase-coherent auditory synthesis under non-stationary acoustic conditions. The framework decouples real-time carrier estimation from phase-coherent signal generation through two specialized modules. An intelligent acoustic sensing module (AI-1) estimates time-varying carrier information across harmonic, fluctuating, and broadband acoustic profiles using a causal neural front-end with an adaptive confidence-driven strategy. A predictive phase-coherent generator (AI-2) then forecasts short-horizon carrier trajectories and drives a discrete-time phase accumulator to maintain continuous phase evolution during binaural beat embedding. Objective evaluation under multiple acoustic profiles and noise conditions shows that the proposed framework maintains strong phase continuity, with a Phase Coherence Factor greater than 0.91, and low artifact levels, with a Signal-to-Artifact Ratio greater than 39.8 dB, under the evaluated conditions. Additional comparisons with conventional DSP baselines, stronger classical F0 estimators, a lightweight neural F0 tracker, and component-wise ablation variants further demonstrate that the performance improvement arises from the combination of adaptive carrier estimation and predictive phase-coherent actuation, rather than from carrier estimation alone. Hardware profiling shows a combined INT8 inference time of 2.4 ms per frame on a resource-constrained Raspberry Pi Zero 2W-class edge device. Importantly, this inference time and the sub-millisecond phase-accumulator resolution should not be interpreted as sub-millisecond end-to-end physical audio latency. The complete system still includes buffering, framing, neural inference, and output processing delay; the proposed method instead reduces effective phase-boundary misalignment through short-horizon predictive compensation. These results support the proposed framework as a lightweight engineering solution for real-time phase-continuous auditory synthesis in dynamic listening environments. The reported PCF and SAR values should be interpreted as signal-level indicators of phase continuity and artifact suppression, rather than as evidence of listener comfort, perceptual preference, or neurophysiological efficacy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Combined effects of double mutations on catalytic activity and structural stability contribute to clinical manifestations of glucose-6-phosphate dehydrogenase deficiency(2021-12-01) ;Pakparnich, Phonchanan ;Sudsumrit, Sirapapha ;Imwong, Mallika; Chamchoy, KamonwanGlucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in humans, affecting ~ 500 million worldwide. A detailed study of the structural stability and catalytic activity of G6PD variants is required to understand how different mutations cause varying degrees of enzyme deficiency, reflecting the response of G6PD variants to oxidative stress. Furthermore, for G6PD double variants, investigating how two mutations jointly cause severe enzyme deficiency is important. Here, we characterized the functional and structural properties of nine G6PD variants: G6PD Gaohe, G6PD Mahidol, G6PD Shoklo, G6PD Canton, G6PD Kaiping, G6PD Gaohe + Kaiping, G6PD Mahidol + Canton, G6PD Mahidol + Kaiping and G6PD Canton + Kaiping. All variants were less catalytically active and structurally stable than the wild type enzyme, with G6PD double mutations having a greater impact than single mutations. G6PD Shoklo and G6PD Canton + Kaiping were the least catalytically active single and double variants, respectively. The combined effects of two mutations were observed, with the Canton mutation reducing structural stability and the Kaiping mutation increasing it in the double mutations. Severe enzyme deficiency in the double mutants was mainly determined by the trade-off between protein stability and catalytic activity. Additionally, it was demonstrated that AG1, a G6PD activator, only marginally increased G6PD enzymatic activity and stability. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Hollow natural rubber latex particles as bio-based alternative white pigment for coating applications(2022-11-15) ;Promlok, Duangkamol ;Sonongbua, Kritayakorn ;Wilepsuwan, Mutita; Tangboriboonrat, PramuanDue to the broad particle size distribution as well as non-spherical shape of natural rubber (NR) latex particles, the non-collapse hollow NR latex particles (HL-NRPs) with well-defined void structure were developed aiming to use as an eco-friendly white pigment/additive for coatings. These hybrid HL-NRPs were prepared via the seeded emulsion polymerization of methyl methacrylate/divinylbenzene/acrylic acid (MMA/DVB/AA) monomers on NR core particles in one-pot. Using cumene hydroperoxide (CHP)/tetraethylene pentamine (TEPA) as a redox initiator, the copolymerization occurred at the particle/water interface. Without seed removal, a single void inside NRP was in situ formed by the phase separation process. Hydrophobic and elastic NR became the inner wall which strengthened the HL particles. Whereas its indigenous stabilizers, i.e., proteins-lipids, allowed the osmosis from the aqueous medium to further expand the void. The proposed mechanism was illustrated using oleic acid (OA) as a model fatty acid for non-rubber substances. Since the multiple light scattering inside the hollow structure could enhance their refractive index, the optical performance of HL-NRPs as a low-density opacifying agent in poly(vinyl alcohol) matrix, was examined using UV-Vis spectroscopy. Results showed that the HL-NRPs-based films exhibited high blocking ability over UV and visible regions. Moreover, the HL-NRPs coated with chitosan (CS) enabled these nanocomposites to adsorb the formaldehyde vapor. For sustainable development, HL-NRPs/CS could potentially be a green alternative white pigment/additive for coatings. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Facile control of structured ZnO polymeric nanoparticles through miniemulsion polymerization: Kinetic and UV shielding effects(2021-08-01) ;Sudjaipraparat, Narissara; Tangboriboonrat, PramuanZinc oxide polymeric nanoparticles (ZPPs) of poly (styrene-co-acrylic acid) P(St/AA), containing oleic acid modified zinc oxide nanoparticles (OA-ZnO NPs), were synthesized via miniemul-sion polymerization. By simply adjusting the quantity of reactants, i.e., sodium dodecyl sulfate (SDS) surfactant, potassium persulfate (KPS) initiator, and divinyl benzene (DVB) crosslinking agent, the location of ZnO NPs were altered from the inner (core) to the outer (shell), leading to core-shell and Pickering-like morphologies, respectively. The Pickering-like ZPPs were obtained when using SDS at below or equal to the critical micelle concentration (CMC). At above the CMC, the complete en-capsulation of OA-ZnO NPs within the ZPPs depicted a kinetically controlled morphology. The transition to Pickering-like ZPPs also occurred when reducing the KPS from 2 to 0.5–1%. Whereas the DVB accelerated the polymerization rate and viscosity in the growing monomer-swollen nanodroplets and, hence, contributed to kinetic parameters on particle morphology, i.e., an increase in the DVB content increased the rate of polymerization. A hollow structure was obtained by replacing styrene with the more hydrophilic monomer, i.e., methyl methacrylate. All ZPPs-incorporated poly (vinyl alcohol) (PVA) films greatly improved shielding performance over the UV region and were relatively transparent on a white paper background. Due to the large number of ZnO NPs in the central region and, hence, the ease of electron transfer, composite films containing core-shell ZPPs possessed the highest UV blocking ability. ZnO NPs in the outer part of the hollow and Pickering-like ZPPs, on the other hand, facilitated the multiple light scattering according to the difference of refractive in-dices between the inorganic shell and organic/air core. These results confirm the advantage of structured ZPPs and their potential use as transparent UV shielding fillers. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Efficacy of sugar excipients on lyophilized C22 phage infectivity evaluated by atomic force microscopy(2022-07-01) ;Manbua, Nathida; Sae-Ueng, UdomBacteriophages (phages) show immense potential as biological control agents of pathogenic bacteria in crops. However, their utilization is hindered by the challenges in storage and handling in remote farming areas. Lyophilization has been used to convert phages from solution to powdery form to overcome such issues. In this work, we lyophilized the C22 phage, a promising biocontrol agent of Ralstonia solanacearum causing wilt disease. Sugar excipients were added during the lyophilization step to preserve phage infectivity. We found that 0.5 M sucrose, 0.25 M, and 0.5 M trehalose could retain infectivity of lyophilized C22 phage for ≥ 45% after 90–day storage. Using atomic force microscopy-based imaging, we revealed that both sugars induced aggregation of C22 phage particles. We suggest that aggregation may be a mechanism that prevents phage from degradation since it reduces overall surface that can unfavorably interact with external damaging factors. An insight into phage aggregation can be essential for phage storage and utilization in biocontrol applications. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, One-Pot Synthesis of Aminated Bimodal Mesoporous Silica Nanoparticles as Silver-Embedded Antibacterial Nanocarriers and CO2Capture Sorbents(2022-11-23) ;Li, Yun ;Tiwari, Amit Kumar ;Ng, Jingyi Sandy ;Seah, Geok LengLim, Hong KitMesoporous silica nanoparticles have highly versatile structural properties that are suitable for a plethora of applications including catalysis, separation, and nanotherapeutics. We report a one-pot synthesis strategy that generates bimodal mesoporous silica nanoparticles via coassembly of a structure-directing Gemini surfactant (C16-3-16) with a tetraethoxysilane/(3-aminopropyl)triethoxysilane-derived sol additive. Synthesis temperature enables control of the nanoparticle shape, structure, and mesopore architecture. Variations of the aminosilane/alkylsilane molar ratio further enable programmable adjustments of hollow to core-shell and dense nanoparticle morphologies, bimodal pore sizes, and surface chemistries. The resulting Gemini-directed aminated mesoporous silica nanoparticles have excellent carbon dioxide adsorption capacities and antimicrobial properties against Escherichia coli. Our results provide an enhanced understanding of the structure formation of multiscale mesoporous inorganic materials that are desirable for numerous applications such as carbon sequestration, water remediation, and biomedical-related applications.
