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Chemical constituents from the fungus Chaetomium cupreum RY202
Author(s)
Date Issued
May 1, 2015
Type
Article
Abstract
Two new angular types of azaphilones, isochromophilonol (1) and ochrephilonol (2), together with ten known compounds (3-12), were isolated from Chaetomium cupreum RY202. Their structures were established on the basis of spectroscopic data and the absolute configurations of 1 and 3 were determined by the modified Mosher's method. Compounds 1, 2 and 4 showed moderated cytotoxicity against KB and NCI-H187 cell lines (IC50 9.63-32.42 μg/mL).
Citation
Archives of Pharmacal Research, 38(5), 585-590, 2015