BODIPY-Based Fluorescent Probes for Selective Visualization of Endogenous Hypochlorous Acid in Living Cells via Triazolopyridine Formation

Peraya Hiranmartsuwan; Sirilak Wangngae; Jukkrit Nootem; Anyanee Kamkaew; Rathawat Daengngern; Worawat Wattanathana; Kantapat Chansaenpak

doi:10.3390/bios12110923

BODIPY-Based Fluorescent Probes for Selective Visualization of Endogenous Hypochlorous Acid in Living Cells via Triazolopyridine Formation

Date

2022-10-25

Authors

Peraya Hiranmartsuwan

Publisher

Biosensors

Abstract

, respectively. This fluorescence enhancement phenomenon could be the effect from C = N isomerization inhibition due to HOCl-triggered triazolopyridine formation. In cell imaging experiments, these compounds showed excellent biocompatibility toward RAW 264.7 murine live macrophage cells and greatly visualized endogenous HOCl in living cells stimulated with lipopolysaccharide.