Nutritional evaluation of santol (Sandoricum koetjape) and the effects of santol flesh extract on Drosophila melanogaster

Santol (Sandoricum koetjape) fruit was low in calories and deficient in vitamins B1, B2, and C, but it is a rich source of potassium, containing 156.05-188.48 mg per 100 g. The first filial (F1) generation was observed on the 3^rd day after emergence, and survival rates exceeded 90% at all concentrations. In climbing assays, a 100 mg/mL concentration reduced climbing speed over a 10 cm distance by 9.35 times in the P generation and 7.74 times in the F1 generation compared to control. At this concentration, the adult emergence rate decreased to 53%, and body weight in both generations was reduced. However, no difference in body weight was observed at concentrations of 20, 40, 60, and 80 mg/mL compared to controls. These findings indicated that santol fruit is a good source of potassium, but high concentrations of santol extract negatively impact the health and performance of D. melanogaster.