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A new xanthone from the fungus Apiospora montagnei

Author(s)
Arthan, Supakorn
Tantapakul, Cholpisut
Kanokmedhakul, Kwanjai
Soytong, Kasem
Kanokmedhakul, Somdej
Date Issued
January 1, 2017
Type
Article
DOI
10.1080/14786419.2017.1290622
Abstract
A new xanthone derivative, methyl 8-hydroxy-3-hydroxymethylxanthone-1-carboxylate (1), and seven known compounds, 8-hydroxy-3-methylxanthone-1-carboxylate (2), methyl 8-hydroxy-6-methylxanthone-1-carboxylate (3), ergosterol (4), cyathisterone (5), ergosta-4,6,8(14),22-tetraen-3-one (6), calvasterone (7) and 2-hexyl-3-methylmaleic anhydride (8) were first isolated from the fungus Apiospora montagnei. Their structures were elucidated on the basis of spectroscopic analysis (UV, IR, MS, 1D, and 2D NMR). Compounds 5 and 6 showed weak to very weak cytotoxicity against cancer cell lines, NCI-H187 and KB.
Citation
Natural Product Research, 31(15), 1766-1771, 2017
Subjects

Apiospora montagnei

cytotoxicity

xanthone

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