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    An investigation on a trachea air flow pattern in an intubated patient: Airway edema case
    (2017-12-19)
    Sanpanich, A.
    ;
    Masomtob, M.
    ;
    Phasukkit, P.
    ;
    Kajornpredanon, Y.
    ;
    Daochai, S.
    In a respiratory failure patient, an artificial ventilation is commonly performed by using a mechanical ventilator particularly in an ICU ward. On such a case, an endotracheal tube (ETT) must be inserted into patient's airway and following by a balloon cuff blowing in order to fix and act as a sealed artificial airway for an artificial ventilation. However, those implementations adversely affect to tracheal tissue-epithelial layer and probably damaging a larynx and vocal cord zone. After a ventilator weaning and an extubating process, some patients always suffering with a larynx or tracheal edema symptom or postextubation stridor (PES) in which patient airway is narrowed or swelling due to a long term pressurization by the ETT balloon cuff. This mainly causes a difficulty in a spontaneous breathing. In general, a cuff leak test is a common medical maneuver used in order to predict a larynx or tracheal edema possibility after ETT was removed. Air volume different between an inspired volume (Vtì) and an expired volume (Vie) normally should be higher than 100 mL or 10%. In this paper, we propose an investigation of an airflow pattern on an intubated patient in the cuff leak test process in order to understand and support a prediction of the tracheal edema before perform an ETT extubation. The study was performed in an intubated trachea by using a simulation of an airflow pattern, air volume prediction in a normal intubated case and during cuff leak test process with no edema and edema case. Although, this simulation was intently implemented in a simple intubated trachea model, however the obtain results imply us a practical information and will be used as a basic implementation for a further study, especially in case of variety in the ETT intubation or cuff less ventilation even more complication case in the near future.
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    Airflow effect on microwave ablation in lung model
    (2016-02-04)
    Phairoh, C.
    ;
    Sanpanich, A.
    ;
    Kajornpredanon, Y.
    ;
    Petsarb, K.
    ;
    Sroykham, W.
    Pulmonary microwave ablation has been trailed and became dramatically recognized as an alternative surgical method for lung cancer treatment due to its minimal invasive technique and destroyable only a small part of malignant tissue. Even though, lung is realized as a porous tissue in which filled of humid air and a capillary network that rather difficult to control an ablation region, then a prediction of lung destructive region by using MWA simulation seem to be a reliable investigation and numerical tool for supporting this medical maneuver. In this paper, we propose a simulation of microwave thermal ablation for lung cancer treatment in a simple lung model. Microwave applicator was designed as an opened-tip coaxial antenna of 2.45 GHz at 10 Watts. To study an effect of air flow in pulmonary bronchus, a small tube with air flow was also placed close to the microwave applicator then a temperature distribution and coagulation volume at 60 °c were analyzed. The in silico results show a predictable ablation shape which affected by a convection heat transfer of a humid air. However, before a real ablation with swine tissue, an amount of pulmonary blood flow in small blood vessel should be also included in the next investigation inorder to obtain more reasonable results.
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    Thermal ablation for cancer treatment by using microwave energy in a simple lung model
    (2014-01-20)
    Sanpanich, A.
    ;
    Khongkhanon, C.
    ;
    Kajornpredanon, Y.
    ;
    Thanangkul, S.
    ;
    Apaiwong, C.
    Lung cancer or pulmonary cancer is one of a dangerous cancer threatening human life since a long time ago. Even though, a conventional surgery is widely accepted as a gold standard for this cancer treatment, however a new medical maneuver still be investigated to perform with this disease. In this paper, we trail a simulation of thermal ablation by using microwave energy at 2.45GHz, 30 Watts for 10 seconds with an opened-ring coaxial applicator in a simple lung tissue model. An air tracheal also placed in this model in order to compare for a thermal distribution. Although, this model is quite differing from a porous material, but our simulation results of temperature distribution and destructive area at 60 □C guide us some useful information for a real ex vivo with swine tissue in the near future work.
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    Bone drilling by using microwave ablation; FEM investigation
    (2013-12-01)
    Phairoh, C.
    ;
    Sanpanich, A.
    ;
    Kajornpredanon, Y.
    ;
    Thanangkul, S.
    ;
    Apaiwong, C.
    Bone drilling by using heat energy from microwave is a promising research issue and has been proposed by some researcher. However, there are still some interesting topics remaining to be investigated especially in term of a temperature variation during burning or drilling process and a prediction of an extreme burning size or drilling diameter. In this paper, we propose an FEM investigation of bone drilling by using microwave thermal ablation emphasizing on a temperature distribution pattern and temperature variation at a hot spot of a cutting-end antenna. Bone phantom was modeled as two solid layers as cortical and bone marrow part. Simulation was implemented in three different applicator positions in bone model as a top surface, middle and near marrow. The obtained simulation results give us useful information to design more suitable and practicable applicator for heat pattern focusing in a compact bone tissue and also encourage us to validate with a bovine bone in near future. © 2013 IEEE.
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    Opened-tip applicator and ex vivo experimental results for microwave breast cancer ablation
    (2012-11-26)
    Sanpanich, A.
    ;
    Kajornpredanon, Y.
    ;
    Phasukkit, P.
    ;
    Tungjitkusolmun, S.
    ;
    Pintavirooj, C.
    Breast cancer is one of the main health hazard that threatening women life all over the world. Not only her own daily life, but also her own family whom suffering from this poor fate. Besides from a breast resection, microwave ablation is also another effective therapeutic technique for glandular tissue cancer treatment due to its minimal invasive maneuver. In this paper, we propose a study of an opened-tip applicator ablation for breast cancer therapy. The investigation was preliminary performed by using finite element method to analyze a characteristic of antenna and to simulate a 2.45 GHz electromagnetic wave phenomenon in living tissue then following by ex vivo experiment with female swine breast. In term of FEM simulation, full 3D distribution pattern of SAR, temperature and also estimated destructive tissue area in a complicated CAD model of cancerous breast was analyzed. Real ablation with an ultrasound-guided applicator insertion was implemented to confirm an effective result. This study not only shows a promising result but also encourage us to develop an advance microwave ablation system in near future. © 2012 IEEE.