Tungjitkusolmun, Supan

Preferred name

Alternative Name

Tungjitkusolmun, S.

Main Affiliation

School of Engineering

supan.tu@kmitl.ac.th

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Combined medical imaging with CFD analysis for application of diagnostic and treatment planning: The case study of human nasal airflow simulation based on CT imaging
(2009-01-01)
Hemtiwakorn, Khaisang
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Phoocharoen, Niwat
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Tungjitkusolmun, Supan
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Mahasittiwat, Visan
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Sangworasil, Manas
The previous methods of human airflow measurement such as rhinomanometry or acoustic rhinometry could not visualize the airflow and calculated the velocity magnitude in specific region of nasal cavity. Thus, this study proposes the combination of CT and CFD analysis of nasal airflow simulation in normal human breathing. This method can demonstrate the airflow direction, and also calculate the velocity magnitude inside the nasal cavity. The processes of this study are segmentation, meshing, solving, and post-processing. Firstly, Mimic 10.01 software was used to segment the nasal cavity. Secondly, Pro-STAR/amm software was used to generate trimmed mesh of 338, 496 elements. Finally, computational grid model was imported to STAR-CD version 3.26 for numerical computation, and visualize the solution by post-processing. The result shows that velocity magnitude of airflow is greatest in nasal valve area which is the narrowest area of the human nose. Also, the flow commonly pass through the main nasal passage and middle meatus areas of nose. Experimental validation will be reported in the further publication. In conclusion, this study is the important begining of an applied CFD analysis with medical imaging. CT imaging combines with CFD analysis could be useful for rhinologist as a nose function evaluation technique. Moreover, the applications of this method could be utilized in a wide range of research topics, especially development of diagnostic and treatment planning techniques.
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Computational fluid analysis of blood flow characteristics in abdominal aortic aneurysms treated with suprarenal endovascular grafts
(2009-12-01)
Sun, Zhonghua
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Chaichana, Thanapong
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Sangworasil, Manas
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Tungjitkusolmun, Supan
The purpose of this study is to investigate the hemodynamic effects of suprarenal stent grafts on the renal arteries in the treatment of patients with abdominal aortic aneurysm. Suprarenal stent grafts have been increasingly used for treatment of aortic aneurysms with suboptimal aneurysm necks. However, the long-term safety of this procedure is yet to be determined. 2 sample patients undergoing suprarenal stent grafting were included in the study. Four variable configurations of stent wires crossing the renal artery ostium were simulated in aorta models based on CT generated data, at different cardiac cycles. The stent wires thickness was set 0.5 mm which is similar to the actual diameter of a stent wire. Computational fluid dynamic analysis showed slightly decrease of flow velocity to the renal arteries with multiple wires crossing, and no changes of flow velocity to the renal arteries with single wire crossing. Our preliminary results demonstrated the safety of suprarenal stent grafting. Further studies are required to investigate the effect of different wire thickness on subsequent hemodynamic changes to the renal arteries.
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Error analysis of tissue resistivity measurement
(2002-04-30)
Tsai, Jang Zern
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Will, James A.
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Stelle, Scott Hubbard Van
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Cao, Hong
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Tungjitkusolmun, Supan
We identified the error sources in a system for measuring tissue resistivity at eight frequencies from 1 Hz to 1 MHz using the four-terminal method. We expressed the measured resistivity with an analytical formula containing all error terms. We conducted practical error measurements with in-vivo and bench-top experiments. We averaged errors at all frequencies for all measurements. The standard deviations of error of the quantization error of the 8-bit digital oscilloscope with voltage averaging, the nonideality of the circuit, the in-vivo motion artifact and electrical interference combined to yield an error of ±1.19%. The dimension error in measuring the syringe tube for measuring the reference saline resistivity added ±1.32% error. The estimation of the working probe constant by interpolating a set of probe constants measured in reference saline solutions added ±0.48% error. The difference in the current magnitudes used during the probe calibration and that during the tissue resistivity measurement caused ±0.14% error. Variation of the electrode spacing, alignment, and electrode surface property due to the insertion of electrodes into the tissue caused ±0.61% error. We combined the above errors to yield an overall standard deviation error of the measured tissue resistivity of ±1.96%.
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A simple laboratory test of music therapy for insufficient sleep
(2016-02-04)
Phasukkit, Pattarapong
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Mahrozeh, Nurhayatee
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Kumngern, Montree
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Tungjitkusolmun, Supan
This article studies the behavior of human sleep found the insufficient sleep problem due to the brain performance. This experiment uses devices such as sleeptracker to save the results of a sleep and electroencephalogram (EEG) to detect brainwaves while enjoying music. However, this study considers only a general sleep and sleep event that a relaxed with the music. The findings indicated the music can help to reduce the problems of insufficient sleep. As a result, volunteers are developing the sleep as sufficiently and efficiently due to get the best quality of sleep in the life. It is also available to deploy to the general person in order to solve the problem of insufficient sleep.
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Length effect of metal-tip monopole antenna to temperature distributions for microwave ablation
(2007-01-01)
Chaichanyut, M.
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Lertprasert, P.
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Phonphruksa, P.
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Tungjitkusolmun, S.
This paper present three-dimensional finite element analyses of hepatic cancer. We studied the characteristics of metal-tip monopole (MTM) antennas for microwave ablation by analyzing the length effect of metal at the antenna tip. We analyses microwave ablation at frequency of 2.45GHz.The length of metallic tip (ht) are varied so as to observe the effect on the temperature distribution. Simulations the length of metallic tip are 1mm, 2mm and 4 mm. From the simulation results, we considered the hepatic cancer region where temperature exceeds 50 °C. The lengths of metallic tip are 1 mm, 2 mm and 4mm had similar temperature distribution profiles and the maximum temperature occurred around the tips of the antennas. In case the length of metallic tip is 4mm, the temperature distribution was widest and induced the highest temperature in cancer tissue. In addition, the temperature distribution was narrowly shaped along the length in regions the shaft body of the antenna. For case the length of metallic tip is 2 mm, the temperature had minimum in cancer tissue and can be minimum ablation cancer tissue (17.34cm3). For case the length of metallic tip is 1 mm, this case can be maximum ablation cancer tissue (18.67cm3).
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Airflow analysis of radiofrequency ablation for asthma therapy by using 3D finite element method
(2013-12-01)
Ruxsapong, P.
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Phasukkit, P.
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Tungjitkusolmun, S.
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Prasantamrongsiri, S.
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Sanpanich, A.
The research aimed to present airflow analysis of radiofrequency ablation for asthma therapy by using three-dimensional finite element method. We study a solution for asthma therapy by using radiofrequency ablation method. Airflow is main factor for asthma therapy. Asthma patients have shortness of breath, coughing, wheezing, and chest tightness that influence a daily life of patients. All symptoms cause to die, especially in severe symptom patients. Asthma therapy by using radiofrequency ablation is a new alternative maneuver to the patient and hopefully may extend his lifetime, reduce using of medicines in asthma treatment and also save money on medical care. The simulation results obtained from our three-dimensional finite element method show airflow that will directly affect the temperature distribution by using radiofrequency ablation technique. These simulation results also guide us to develop an advance asthma treatment in the future. © 2013 IEEE.
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Patient-specific aided surgery approach of deviated nasal septum using computational fluid dynamics
(2015-05-01)
Hemtiwakorn, Khaisang
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Mahasitthiwat, Visan
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Tungjitkusolmun, Supan
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Hamamoto, Kazuhiko
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Pintavirooj, Chuchart
In treating a patient with deviated nasal septum (DNS), a surgeon draws up a surgical plan based on the patient's rhinomanometry outcomes and self-assessment of nose conditions, e.g. the nasal obstruction septoplasty effectiveness (NOSE) score. However, the procedure fails to localize the DNS and determine the nose's aerodynamic effects. This paper proposes a DNS-aided surgery approach using computational fluid dynamics (CFD) and computed tomography (CT) techniques consisting of three main processes: preoperative, presurgical planning, and postoperative processes. The healthy baseline refers to a benchmark consisting of five subjects without DNS and nasal airway obstructions. To assess the possibility of using the CFD-CT-aided surgery approach as a presurgical planning tool in the DNS operation, comparative tests were carried out with DNS patient #1, who received a conventional nasal surgery without the proposed presurgical planning. Although DNS patient #1's surgical outcome was relatively satisfying to the patient, evaluating from the reduction of the NOSE score the conventional surgical method could induce an excessive excision of nasal airway, resulting in water loss in the nasal mucosa and a large reduction in airflow velocity. In addition, the postoperative nasal resistance measured by a rhinomanometer was not acceptable to the surgeon. Virtual surgery using the CFD-CT approach performed after surgery could suggest suitable patient-specific components of nasal operation with predictable results. Subsequently, implementation of the proposed CFD-CT approach in aid of DNS surgery was performed in DNS patient #2. The benefits of the CFD-CT-aided surgery approach were determined based on the pre- and postoperative outcomes (i.e. nasal geometric data and nasal airflow patterns), NOSE scores, and rhinomanometric data of DNS patient #2, which were compared against those of the healthy baseline benchmark. The CFD-CT approach could assist the surgeon to localize the DNS and determine the defective nasal tissues to be removed. The actual postoperative outcomes were clinically acceptable to the surgeon and DNS patient #2. It is evident that the CFD-CT-aided surgery approach is suitable for and applicable to surgery of DNS patients with small variability from the presurgical planning stage.
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Automated segmentation of infarct lesions in t1‐weighted mri scans using variational mode decomposition and deep learning
(2021-03-02)
Paing, May Phu
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Tungjitkusolmun, Supan
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Bui, Toan Huy
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Visitsattapongse, Sarinporn
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Pintavirooj, Chuchart
Automated segmentation methods are critical for early detection, prompt actions, and immediate treatments in reducing disability and death risks of brain infarction. This paper aims to develop a fully automated method to segment the infarct lesions from T1‐weighted brain scans. As a key novelty, the proposed method combines variational mode decomposition and deep learning-based segmentation to take advantages of both methods and provide better results. There are three main technical contributions in this paper. First, variational mode decomposition is applied as a pre-processing to discriminate the infarct lesions from unwanted non‐infarct tissues. Second, overlapped patches strategy is proposed to reduce the workload of the deep‐learning‐based segmentation task. Finally, a three‐dimensional U‐Net model is developed to perform patch‐wise segmentation of infarct lesions. A total of 239 brain scans from a public dataset are utilized to develop and evaluate the proposed method. Empirical results reveal that the proposed automated segmentation can provide promising performances with an average dice similarity coefficient (DSC) of 0.6684, intersection over union (IoU) of 0.5022, and average symmetric surface distance (ASSD) of 0.3932, respectively.
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Finite element analysis on phase shift effect of multi-antenna array alignment for microwave liver ablation
(2012-12-01)
Phasukkit, P.
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Tungjitkusolmun, S.
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Sanpanich, A.
Microwave ablation for liver cancer treatment has been widely performed due to its minimal invasive technique both single and multi probe. Even though, multi antenna ablation system provide a larger destroy area, however effect of phase shift difference between each antenna is still challenge to be investigate for total ablation result. In this research, we propose a preliminary investigate of phase shift effect to a multi antenna system. Two probes array and three probes array was configured as a multi antenna liver ablation system based on each coaxial opened-slot antenna. By using FEM analyze, we present a full 3D simulation results of those multiple antenna system as phase shift between each probe was varied. Total destroy volume is effected significantly when phase shift was differed from 90°, 180° and 270°. © 2012 IEEE.
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In vivo electrical conductivity of hepatic tumours
(2003-01-01)
Haemmerich, Dieter
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Staelin, S. T.
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Tsai, J. Z.
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Tungjitkusolmun, S.
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Mahvi, D. M.
Knowledge of electrical tissue conductivity is necessary to determine deposition of electromagnetic energy and can further be used to diagnostically differentiate between normal and neoplastic tissue. We measured 17 rats with a total of 24 tumours of the K12/TRb rat colon cancer cell line. In each animal we measured in vivo hepatic tumour and normal tissue conductivity at seven frequencies from 10 Hz to 1 MHz, at different tumour stages between 6 and 12 weeks after induction. Conductivity of normal liver tissue was 1.26 ± 0.15 mS cm-1 at 10 Hz, and 4.61 ± 0.42 mS cm-1 at 1 MHz. Conductivity of tumour was 2.69 ± 0.91 mS cm-1 at 10 Hz, and 5.23 ± 0.82 mS cm-1 at 1 MHz. Conductivity was significantly different between normal and tumour tissue (p < 0.05). We determined the percentage of necrosis and fibrosis at the measurement site. We fitted the conductivity data to the Cole-Cole model. For the tumour data we determined Spearman's correlation coefficients between the Cole-Cole parameters and age, necrosis, fibrosis and tumour volume and found significant correlation between necrosis and the Cole-Cole parameters (p < 0.05). We conclude that necrosis within the tumour and the associated membrane breakdown is likely responsible for the observed change in conductivity.

Tungjitkusolmun, Supan

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