Monvisade, Pathavuth
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Preferred name
Monvisade, Pathavuth
Alternative Name
Monvisade, P.
Main Affiliation
Email
pathavuth.mo@kmitl.ac.th
29 results
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Item type:Publication, Colorimetric Screen-Printed Label Using Low Molecular Weight Chitosan Grafted with Rosolic Acid for pH and Ammonia Gas Sensing(2024-10-15) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Photocrosslinked Poly(Vinyl Alcohol)–Tung Oil–Natural Rubber Films: A Sustainable Solution for Enhanced Water Resistance and Mechanical Properties in Biodegradable Packaging(2025-06-20); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Bacterial cellulose and bacterial cellulose/chitosan films containing mangosteen pericarp extract for wound dressings(2021-01-01); Appropriate wound dressings for maintaining a moist wound environment, inducing re-epithelialization and protection from infection have been widely developed. Recently, many biocompatible polymers and bioactive substances have been extensively used for wound healing applications. In this study, bacterial cellulose film (BC-MPE film) and bacterial cellulose/chitosan film (BC/CH-MPE film) containing 1.56 mg/mL of mangosteen pericarp extract (MPE) were prepared. Antibacterial activity, cytotoxicity, physical and mechanical properties of the dry films were investigated. The BC film with MPE presented non-cytotoxic effect after 20 h of exposure to mouse fibroblast cell line (L929). The prepared films performed carrier of bioactive compounds that exhibited antibacterial activity against bacterial infection in burn wounds. The morphology of the films showed the characteristic of ultra-fine network structures with the entrapment of compounds. In addition, the compact structure was observed due to the rapid moisture loss during vacuum drying process. SEM images also showed that BC/CH-MPE film formed layers with chitosan entrapment causing the film to become thicker than BC-MPE film. The formation of MPE and chitosan in modified films was also confirmed by FTIR. The compact structure of BC/CH-MPE film led to the decrease in cumulative release of xanthone, WVTR and WAC. Moreover, the existence of chitosan in BC layers provided more flexible properties than the non-chitosan film. The chitosan addition demonstrated an influence of barrier film to protect the wound. Therefore, BC and chitosan were considered as suitable candidates for wound dressing material and xanthone content of MPE promoted wound healing as an effective therapeutic agent. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Antimicrobial nanolayer films of chloroxylenol–carboxyethylchitosan–modified silver nanoparticles for enhanced surgical suture performance(2024-07-20); ; Antimicrobial surgical suture materials incorporating chloroxylenol-carboxyethylchitosan-modified silver nanoparticles (CECSX-AgNPs) were successfully prepared using the Layer-by-Layer (LbL) deposition technique. Chitosan (CS) was covalently affixed with chloroxylenol as hydrophobic functional groups (PCMX), yielding chloroxylenol-chitosan (CSX) and later hydrophilic acrylic acid onto the CSX skeleton, providing a novel water-soluble antimicrobial agent of chloroxylenol-carboxyethylchitosan (CECSX). <sup>1</sup>H NMR confirmed the successful substitution of PCMX and acrylic acid onto CS, with %DS<inf>PCMX</inf> and %DS<inf>AA</inf> of 8.0 and 33.0, respectively. CECSX successfully stabilized AgNPs via the chemical reduction method, resulting in CECSX modified AgNPs. The colloidal solution exhibited a yellowish hue, spherical shape, monodispersity with an average particle size of 4.8 ± 2.4 nm, and a zeta potential value of −20.97 ± 0.03 mV. Minimum inhibitory concentration (MIC) values for CECSX-AgNPs against E. coli (ATCC25922), S. aureus (ATCC25923), and A. baumanii (ATCC19606) were determined as 25, 12.5, and 1.56 mg/L, respectively. Using the LbL deposition technique, CECSX-AgNPs were successfully deposited onto various suture materials including cotton, polyamide, and polypropylene. Remarkably, CECSX-AgNPs coated surgical sutures exhibited the highest bacterial reduction of 99.99 %. These findings underscore the efficacy of CECSX as a high-performance stabilizing agent for AgNPs production, providing outstanding antibacterial activity on diverse surgical suture materials and promoting the wound healing process. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Development of Bilayer Chitosan–Carrageenan Hydrogel Film for Enhanced Controlled Release of Turmeric–β-Cyclodextrin Complex in Wound Dressings(2025-11-01); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, New Chitosan-Grafted Thymol Coated on Gold Nanoparticles for Control of Cariogenic Bacteria in the Oral Cavity(2022-08-02); ; Chitosan-grafted thymol (CST) coated on gold nanoparticles has been synthesized and characterized for the design of antimicrobial materials. CST was synthesized via adapting the Mannich reaction, and it acted as the capping agent for the synthesis of gold nanoparticles (AuNPs). The grafting of thymol onto the side chain of chitosan has provided a degree of substitution value (%DS<inf>NMR</inf>) of 10.0%, calculated by nuclear magnetic resonance spectroscopy. UV-visible spectrometry and elemental analysis were used to confirm the successful synthesis of CST through adapting the Mannich reaction. The appropriate concentration of CST for AuNP synthesis was found to be 0.020%w/v. A red-wine colloidal AuNP solution of 2.41-3.30 nM particle size exhibits a strong surface plasmon resonance at 502 nm, which shows negative charges at pH = 9 of -36.37 mV. This result evidenced that the AuNPs showed electrostatic repulsion and CST played a role as a capping agent to provide a good dispersion and stability state. CST coated on the AuNP surface was successfully utilized for the control of cariogenic bacteria in the oral cavity. The results obtained from this study show that the tuning of the capping agent used in the synthesis step strongly influences the latter antimicrobial activity of the nanoparticles against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33402 activity, with an inhibition zone of 15.90 and 14.25 mm, respectively. The average minimum inhibitory concentration values against S. mutans ATCC 25175 and S. sobrinus ATCC 33402 were found to be 25 and 100 mg/L, respectively, whereas the minimum bactericidal concentration values were 100 and 200 mg/L, respectively. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Silver loaded hydroxyethylacryl chitosan/sodium alginate hydrogel films for controlled drug release wound dressings(2020-09-15) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Enhancing chitosan solubility in alcohol: water mixtures for film-forming systems releasing with turmeric extracts(2021-06-01); Background: Film-forming system (FFS), a non-solid dosage form, are attractive drug delivery system for the topical drug administration due to ability to form a film in situ on a skin after spraying or applying. To minimize drying time, alcohol is often used as a solvent in the system. The aim of this research was to enhance chitosan solubility in alcoholic solution by chemical modification of chitosan, i.e., reductive amination and Michael addition reaction, for film-forming systems with efficient releasing of turmeric extract. Methods: Alcoholic-soluble chitosan derivative (CBA) was synthesized by reductive amination, followed by a Michael reaction. Its structure was investigated by FT-IR, <sup>1</sup>H NMR and XRD techniques. The CBA was incorporated with β-cyclodextrin encapsulated turmeric extract (CDTE) to prepare film-forming solution. Significant Findings: The results confirmed that the CBA was successful prepared, as the new peaks were observed by FT-IR and <sup>1</sup>H NMR, with good solubility in 50% aqueous alcoholic solution. The CBA-based film, derived from the solvent evaporation, exhibited nontoxic to HaCaT cells. Moreover, the films containing CDTE had smooth surfaces and released turmeric extract (74%) more effectively than films containing the extract alone (43%). The CBA-based ethanolic solution (30–50%v/v ethanol) could dry within ~6–9 min and form a thin film on human skin. Conclusions: Thus, the CBA-based solution with CDTE has potential as a film-forming system based on natural products. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Development of a pH-responsive intelligent label using low molecular weight chitosan grafted with phenol red for food packaging applications(2024-05-01) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Dual covalent and ionic crosslinked xanthan gum–PVA hydrogel films for enhanced drug release performance(2025-11-01);