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    Remote Temperature Monitoring for Infant Incubator using Thermal Camera
    (2022-01-01)
    Chuenpirom, Thanaporn
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    Health concerns over the premature babies are their immature organs and low birth weight. As a result, these babies may have difficulty in breathing, maintaining their healthy body temperature or being light sensitive. Infant incubator has been designed to overcome these issues. It is a medical device that could provide healthy environment, such as light, temperature and humidity. Moreover, it is also able to control and detect any changes which affect the baby's health. Health monitoring systems are critical in modern incubators, which could involve a set of sensors to read and send physiological information, such as temperature. It has also been proposed that establishing remote monitoring system via global system for mobile communications (GSM) would be beneficial for the incubators as it could send an alarm to the doctors and parents in the event that unhealthy vital parameters have been detected. Although a variety of vital parameters are included in the monitoring features of some modern incubators, the capability to detect body temperature of the babies are limited. Hence, this project proposes the development of an effective low-cost smart infant incubator that will benefit the body temperature monitoring of newborn babies using remote IoT-based monitoring system. The monitoring system is controlled through the use of a Raspberry Pi attached to a visual camera and a thermal IR camera with temperature sensor MLX90640, which was able to measure the body temperature remotely. The software of this smart infant incubator was used to improve monitoring system, which involves image processing techniques. The results of measured ambient temperature were found to be accurate and reliable. The prototypical incubator has been designed and manufactured with affordable cost, and the control system of the incubator was able to work comparably to other incubators with potential capability to measure body temperature of the infant.
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    Effects of Surface Finishing Techniques on Properties of NiTi Coil Spring Actuators
    (2025-01-01)
    Premwattananarakul, Natakorn
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    Kumnorkaew, Theerawat
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    Phukaoluan, Aphinan
    This research aims to investigate the effects of surface finishing techniques on phase transformation, topography, and recovery force of NiTi coil springs designed for actuator applications. The NiTi wire, with a diameter of 1 mm, was fabricated into a helical spring with an index of 9 and 20 active coils. The spring was subsequently annealed at 550 °C for 30 min and then quenched in water. The surface finishing techniques applied to the NiTi springs included chemical etching, mechanical polishing, and sand blasting. It was observed that mechanical polishing had a strong impact on topography than both chemical etching and sand blasting. After mechanical polishing, the topography of NiTi coil springs slightly changed compared to the annealed spring. The examined surface was smooth and glistening, with a surface roughness R<inf>a</inf> of 0.175 ± 0.006 µm, nearly identical to that of the annealed spring R<inf>a</inf> of 0.116 ± 0.021 µm. Chemical etching produced a surface oxide, yet the surface became rough due to an uncontrollable chemical reaction, i.e., the R<inf>a</inf> value obtained from chemical etched surface (1.177 ± 0.156 µm) was higher than that of the mechanically polished spring. Meanwhile, sand blasting provided a blue-shaded surface corresponding to an excessive R<inf>a</inf> of 1.952 ± 0.204 µm. The DSC results revealed two peaks of R-phase and martensite transformation in the cooling curve, with only austenite transformation appearing on the heating curve. According to the DSC curve, all surface finishing techniques can reduce the latent heat and affect the associated phase transformations. Consequently, the recovery force of the spring was increased by 2–5 times the initial length. The maximum stiffness (k) of 0.129 N/mm and recovery force for the surface-finished springs were provided by mechanical polishing, while the minimum values of 0.104 N/mm were yielded by sand blasting. All experimental findings offer a framework for the development of actuator springs enhanced through each surface finishing technique.
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    Assessment of the Utility of Chitosan in Drug Delivery of Sulfamethoxazole
    (2024-01-01)
    Soontorntepwarakul, Nussara
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    The objective of this research was to develop chitosan (CS) nanoparticles (NP) and microfibres (MF) for oral delivery applications related to low solubility drugs. The ionic gelation method in conjunction with freeze-drying was used to produce crosslinked chitosan material. Dynamic light scattering (DLS) was used to characterize particle size and polydispersity index (PDI). Surface morphology was analyzed using scanning electron microscopy (SEM). The antibiotic drug sulfamethoxazole (SMO) was loaded onto the chitosan nano/micro material. The degree of loading, loading efficiency and the release kinetics were investigated using high-performance liquid chromatography (HPLC) and UV-visible spectrophotometry, respectively. We found that CS nanoparticles have the potential to improve the delivery properties of SMO due to their more rapid release compared to microfibres or traditional tablet formulations.
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    Fabrication of Water-insoluble Polyethylene Oxide and Sodium Alginate using Electrostatic Repulsive Forces: A Preliminary Study
    (2023-01-01)
    Niyomchon, Phuphinee
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    Polyethylene oxide (PEO) and sodium alginate (NaAlg) are widely used in biomedical applications due to their biocompatibility. The use of electrostatic repulsive forces could be employed to fabricate these polymers into various shapes, including fibers and particles. However, in some cases, their solubility in water could be a drawback. Therefore, this study aims to fabricate samples from PEO-NaAlg blends using electrostatic repulsive forces and stabilize their structure in water using calcium chloride (CaCl<inf>2</inf>) crosslinking method. The preliminary results have shown that the water solubility of the fabricated samples in this study was reduced by crosslinking, as analyzed by Fourier-transform spectroscopy (FTIR). Moreover, the images from scanning electron microscope (SEM) reveal that the fabricated samples were particle-like, and the increased NaAlg content could increase fiber density before crosslinking and particle aggregate formation after crosslinking. However, further studies are still required to optimize the parameters for fiber fabrication and also for future incorporation of bioactive molecules.
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    The Addition of Fluoride to the Eggshell-derived Hydroxyapatite: A Preliminary Study
    (2021-01-01)
    Uthayaphamornwat, Vilasinee
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    Suksap, Arissara
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    Khantachawana, Anak
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    Dental caries are one of the major oral health problems, which could be mitigated by addressing the dental defects. Hydroxyapatite (HA) is commonly used for tooth and bone replacement due toits similar properties as the native hard tissues. Natural sources with abundant availability, such as eggshells, could be used to synthesize HA. Moreover, with the presence of fluorine in HA, it was suggested that the performance of this material could be enhanced in terms of material stability and anti-caries properties. This preliminary study aims to compare two methods used to produce fluoride-added HA from eggshells, which are pH cycling and wet precipitation methods. The molecular structure, crystal structure, particle appearance and chemical compositions of the obtained samples were characterized. The results suggested that pH cycling has provided samples with higher fluorine content, more crystalline structure and less CO3than those obtained from wet precipitation method. Therefore, pH cycling method appears to be more suitable for further processing and characterization of the fluoride-added HA samples derived from eggshells.
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    Characterization of Fluoride-added Hydroxyapatite Derived from Eggshells for Dental Application
    (2023-01-01)
    Uthayaphamornwat, Vilasinee
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    Khantachawana, Anak
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    Hydroxyapatite (HA) is one of the potential biomaterials used for treating dental defects. It can be incorporated with fluoride to enhance its anti-caries properties, though other properties could be dependent on processing technique. Hence, this study aims to characterize the influence of sintering on the properties of fluoride-added HA derived from eggshells. FTIR and XRD techniques are used to characterize the chemical and crystal structures of the samples, whilst dissolution test is carried out to characterize material degradation in the acidic environment. The results show that sintering increased the crystallinity in both HA and fluoride-add HA (F-HA) samples, which corresponds with the enhanced stability during the dissolution test. Moreover, it is also found that the addition of fluoride could further stabilize the material structure, though the impurities found in all the samples still need to be minimized. These findings suggest that sintering and fluoride addition could potentially enhance anti-caries properties of eggshell-derived HA, which could be beneficial for dental application in future subject to further process optimization and analysis.