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Automatic detection of pulmonary nodules using three-dimensional chain coding and optimized random forest

Author(s)
Paing, May Phu
Hamamoto, Kazuhiko
Tungjitkusolmun, Supan
Visitsattapongse, Sarinporn
Pintavirooj, Chuchart
Date Issued
April 1, 2020
Type
Article
DOI
10.3390/app10072346
Abstract
The detection of pulmonary nodules on computed tomography scans provides a clue for the early diagnosis of lung cancer. Manual detection mandates a heavy radiological workload as it identifies nodules slice-by-slice. This paper presents a fully automated nodule detection with three significant contributions. First, an automated seeded region growing is designed to segment the lung regions from the tomography scans. Second, a three-dimensional chain code algorithm is implemented to refine the border of the segmented lungs. Lastly, nodules inside the lungs are detected using an optimized random forest classifier. The experiments for our proposed detection are conducted using 888 scans from a public dataset, and achieves a favorable result of 93.11% accuracy, 94.86% sensitivity, and 91.37% specificity, with only 0.0863 false positives per exam.
Citation
Applied Sciences Switzerland, 10(7), 2020
Subjects

3D chain code

Automated seeded regi...

Firefly

Lung cancer

Pulmonary nodule

Random forest

Metrics
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