Now showing 1 - 10 of 15
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Superparamagnetic nanoparticles encapsulation via droplet-based microfluidics for targeted drug delivery system
    (2019-01-01) ;
    Sukthai, Ratchanont
    ;
    ;
    Suktham, Kunat
    ;
    Klamchuen, Annop
    Here, we present monodispersed superparamagnetic iron oxide nanoparticles (SPIONs)-loaded poly(lactic-coglycolic acid) (PLGA) microdroplets encapsulation by a microfluidic flow-focusing device. SPIONs in PVA solution were employed as a continuous phase and the mixture of PLGA in dichloromethane (DCM) was employed as a disperse phase in the droplet-based microfluidic system. The diameter of microdroplet was carefully controlled and optimize by flow ratio between the dispersed phase and the continuous phase in the microfluidic system. The formation of monodispersed SPIONs-loaded PLGA microdroplet is a matrix particle structure. The magnetization property of microdroplets was characterized and the external magnetic field induced microdroplet also was performed.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires
    (2017-12-01)
    Yasui, Takao
    ;
    Yanagida, Takeshi
    ;
    Ito, Satoru
    ;
    Konakade, Yuki
    ;
    Takeshita, Daiki
    Analyzing microRNAs (miRNAs) within urine extracellular vesicles (EVs) is important for realizing miRNA-based, simple, and noninvasive early disease diagnoses and timely medical checkups. However, the inherent difficulty in collecting dilute concentrations of EVs (<0.01 volume %) from urine has hindered the development of these diagnoses and medical checkups. We propose a device composed of nanowires anchored into a microfluidic substrate. This device enables EV collections at high efficiency and in situ extractions of various miRNAs of different sequences (around 1000 types) that significantly exceed the number of species being extracted by the conventional ultracentrifugation method. The mechanical stability of nanowires anchored into substrates during buffer flow and the electrostatic collection of EVs onto the nanowires are the two key mechanisms that ensure the success of the proposed device. In addition, we use our methodology to identify urinary miRNAs that could potentially serve as biomarkers for cancer not only for urologic malignancies (bladder and prostate) but also for nonurologic ones (lung, pancreas, and liver). The present device concept will provide a foundation for work toward the long-term goal of urine-based early diagnoses and medical checkups for cancer.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Improved Efficiency of Polymer Solar Cells by means of Coating Hole Transporting Layer as Double Layer Deposition
    (2017-10-20)
    Chonsut, T.
    ;
    ; ; ;
    Polymer solar cells is one of the promising technologies that gain tremendous attentions in the field of renewable energy. Optimization of thickness for each layer is an important factor determining the efficiency of the solar cells. In this work, the optimum thickness of Poly(3,4-ethylenedioxythione): poly(styrenesulfonate) (PEDOT:PSS), a famous polymer widely used as hole transporting layer in polymer solar cells, is determined through the analyzing of device's photovoltaic parameters, e.g. short circuit current density (J<inf>sc</inf>), open circuit voltage (V<inf>oc</inf>), fill factor (FF) as well as power conversion efficiency (PCE). The solar cells were prepared with multilayer of ITO/PEDOT:PSS/PCDTBT:PC<inf>70</inf>BM/TiO<inf>x</inf>/Al by rapid convective deposition. In such preparation technique, the thickness of the thin film is controlled by the deposition speed. The faster deposition speed is used, the thicker film is obtained. Furthermore, double layer deposition of PEDOT:PSS was introduced as an approach to improve solar cell efficiency. The results obviously reveal that, with the increase of PEDOT:PSS thickness, the increments of J<inf>sc</inf> and FF play the important role to improve PCE from 3.21% to 4.03%. Interestingly, using double layer deposition of PEDOT:PSS shows the ability to enhance the performance of the solar cells to 6.12% under simulated AM 1.5G illumination of 100 mW/cm<sup>2</sup>.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Modification of a photoanode by means of localized surface plasmon resonance from Au nanoparticles decorated on ZnO nanorods for photoelectrochemical applications
    (2019-01-01) ;
    Soyeux, Nathan
    ;
    Rattanawarinchai, Prapakorn
    ;
    Jessadaluk, Sukittiya
    ;
    Klamchuen, Annop
    Photoelectrochemical (PEC) activity is possibly enhanced by an increase in photocurrent generated from the photoanode. In this work, a modified photoanode that consists of zinc oxide nanorods (ZnO-NRs) decorated with gold nanoparticles (Au-NPs) is proposed to improve the generation of photocurrent. X-ray diffraction and scanning electron microscopy are employed to confirm the decoration of Au-NPs on well-aligned ZnO-NRs. A significant enhancement (∼4 times) in photocurrent density is obtained from the ZnO-NR photoanode decorated with Au-NPs compared to the bare ZnO-NR photoanode. Photoluminescence and UV-visible spectroscopy reveal that the improvement in photocurrent density results from (i) the decrease in charge recombination in the ZnO-NRs due to charge dissociation and (ii) the additional injection of charge from Au-NPs owing to localized surface plasmon resonance. This research presents the idea of taking the benefit from Au-NPs to enhance the photocurrent density in PEC applications through the decrease in charge recombination and the increase in charge injection.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    A disposable polydimethylsiloxane microdevice for DNA amplification
    (2010-02-05)
    Lekwichai, A.
    ;
    Porntheeraphat, S.
    ;
    Bunjongpru, W.
    ;
    Sripumkhai, W.
    ;
    Supadech, J.
    In this study, we demonstrate the disposable polydimethylsiloxane (PDMS) microchip provided for DNA amplification. The device consists of two main parts. The first part is PDMS/glass stationary chamber, the other part is a temperature-control microdevice on SiO<inf>2</inf>/Si substrate. This device consists of a thin film Pt-microheater and a Pt-temperature sensor, which were fabricated with CMOS compatible process. The performance of the device in the DNA amplification shows that, with 10 μl of PCR mixture volume, the approximately 700 bp DNA were successfully amplified within 50 minutes by 30 PCR cycles. The amplified products were comparable with those of a conventional method using electrophoresis. The PCR chip is also suitable for mass production. © (2010) Trans Tech Publications.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Study of optical and electrical properties of tin doped cobalt-phthalocyanine thin films prepared by thermal co-evaporation
    (2018-09-05) ;
    Jessadaluk, Sukittaya
    ;
    ; ;
    The aim of this research is to study the specific properties e.g. surface morphology, optical absorption as well as electrical conductivity of tin-doped cobalt-phthalocyanine (CoPc) thin film prepared by thermal co-evaporation. The concentration of tin metal dopant is controlled via evaporation rate during film's preparation. The change of tin quantity leads to the significant changes not only in morphology but also in molecular packing of the doped films. Moreover, the dramatic increase in both carrier mobility and carrier concentration should provide the enhancement in electrical conductivity of the doped films. By controlling the specific properties of the tin-doped CoPc thin film, the increasing efficiency of optoelectronic applications based on metal-phthalocyanine could be achieved.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Phase formation polycrystalline vanadium oxide via thermal annealing process under controlled nitrogen pressure
    (2017-10-20)
    Jessadaluk, S.
    ;
    ; ; ;
    This article provides an approach to improve and control crystal phases of the sputtering vanadium oxide (V<inf>x</inf>O<inf>y</inf>) thin films by post-thermal annealing process. Usually, as-deposited V<inf>x</inf>O<inf>y</inf> thin films at room temperature are amorphous phase: post-thermal annealing processes (400 °C, 2 hrs) under the various nitrogen (N<inf>2</inf>) pressures are applied to improve and control the crystal phase of V<inf>x</inf>O<inf>y</inf> thin films. The crystallinity of V<inf>x</inf>O<inf>y</inf> thin films changes from amorphous to α-V<inf>2</inf>O<inf>5</inf> phase or V<inf>9</inf>O<inf>17</inf> polycrystalline, which depend on the pressure of N<inf>2</inf> carrier during annealing process. Moreover, the electrical resistivity of the V<inf>x</inf>O<inf>y</inf> thin films decrease from 10<sup>5</sup> Ω cm (amorphous) to 6×10<sup>-1</sup> Ω cm (V<inf>9</inf>O<inf>17</inf>). Base on the results, our study show a simply method to improve and control phase formation of V<inf>x</inf>O<inf>y</inf> thin films<inf>.</inf>
  • Some of the metrics are blocked by your 
    Item type:Publication,
    A tunable thermal switching device based on Joule heating-induced metal-insulator transition in VO2 thin films via an external electric field
    (2019-01-01)
    Jessadaluk, Sukittaya
    ;
    ;
    Rattanawarinchai, Prapakorn
    ;
    ;
    A solid state thermal switching device can regulate carrier transport by triggering of its critical transition temperature (T<inf>c</inf>) by applied external thermal energy. Continuous control of the T<inf>c</inf> of the thermal switch by the metal-insulator transition (MIT) phenomenon makes such devices widely usable. In this research, tunable thermal switching devices were fabricated, and characterization of the MIT in VO<inf>2</inf> thin film phase transition material was studied as a function of temperature and the external applied electric field. We observed reversible abrupt changes of the electrical resistivity by approximately three orders of magnitude at T<inf>c</inf> = 62.3 °C for VO<inf>2</inf> thin film on a SiO<inf>2</inf>/Si substrate. The MIT induced by the external electric field successfully controlled the T<inf>c</inf> of the thermal switch between 60 °C and 47 °C (as a linear relationship). We found that the Joule heating effect, rather than electric field breakdown, was a dominant mechanism due to the configuration of the device.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Influence of the annealing temperature on the organometallic halide perovskite phase formation via CH3NH3Cl as additive in sequential deposition process.
    Organometallic halide perovskite materials with the general formula ABX<inf>3</inf> have been recently interested as active layers in perovskite solar cells. It is well known that the O<inf>2</inf> is the main problem for fabricated perovskite solar cells. Usually, the perovskite thin film need to be prepared in the N<inf>2</inf> atmosphere or in the glove box. In this research, the metal halide perovskite CH<inf>3</inf>NH<inf>3</inf>PbI<inf>2</inf>Cl thin films were successfully deposited using spin-coating technique via a single step solution deposition and CH<inf>3</inf>NH<inf>3</inf>Cl as additive in sequential deposition process in the open air. The effect of annealing temperature on the organolead halide perovskite phase formation of CH<inf>3</inf>NH<inf>3</inf>PbI<inf>2</inf>Cl thin film was investigated. The phase formation as well as crystal structure were investigated by X-ray diffractometer, and we found that organolead halide perovskite thin film exhibited a pure phase perovskite without the unwanted phases. The crystallinity of the perovskite thin film was enhanced significantly by increasing the annealing temperature, and a single phase of the perovskite phase was observed by increment of the annealing temperature that is above 100<sup>O</sup>C. In addition to this, the growth of crystallinity in the halide perovskite thin film was increased with increasing heat treatment temperature. Furthermore, the morphology variation of the thin films were examined by Field Emission Scanning Electron Microscopy.
  • Some of the metrics are blocked by your 
    Item type:Publication,
    Modification of the optical properties of polydimethylsiloxane (PDMS) for photonic crystal biosensor application
    (2010-05-05) ;
    Saekow, Bunpot
    ;
    Porntheerapat, Suppanit
    ;
    ;
    Hruanun, Chandech
    The sensitivity of a photonic crystal optical biosensor device can be enhanced through the difference in effective refractive index of dielectric materials. In this work, we report the optical modification of refractive index of PDMS from 1.41 to above, by incorporating the additive materials to enhance the sensitivity of photonic crystal optical biosensor devices. The refractive index of mixed-PDMS materials are measured by ellipsometry technique. The surface and cross section morphologies are characterized by Field-Emission Scanning Electron Microscope (FESEM) and Atomic Force Microscope (AFM). The grating structure of 800 nm period PDMS with low refractive index was fabricated by Nano-Imprinting Lithography (NIL) then the mixed-PDMS with high refractive index was spun on the periodic PDMS as photonic crystal device. The sensitivity of devices is characterized and demonstrated by reflection spectra intensity of fluids on surface of the devices. ©2010 IEEE.